MultiOrgan Multi-Parametric MRI Study | NCT04137705 | Trialant

MultiOrgan Multi-Parametric MRI Study | NCT04137705 | Trialant

Arms/Interventions Module

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Multiparametric MRI	Other	A standardised MRI protocol that provides a number of quantitative metrics on liver and other organs relevant to type 2 Diabetes - pancreas, kidneys, spleen, heart, lungs and aorta

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Assessment of repeatability (precision under the same conditions in the same subjects: 2 separate MRI acquisitions on the same scanner) of body composition and multiple organ metrics.	To determine the repeatability of multiparametric MRI in the assessment of body composition and multiple organ structures obtained within a single MR scanning session (liver, pancreas, aorta, heart, kidney, lungs and spleen)	24 months

Secondary Outcomes

Measure	Description	Time Frame
Assessment of the reproducibility (precision under different measurement conditions: same participants scanned on separate MRI scanners at both 1.5T and 3T) of multiparametric MRI for the assessment of body composition and multiple organ metrics.	To determine the reproducibility of multiparametric MRI in the assessment of body composition and multiple organ structures (liver, pancreas, aorta, heart, kidney, lungs and spleen) obtained within separate MR scanning sessions.

Other Outcomes

Measure	Description	Time Frame
Assessment of the mean differences in body composition and multiple organ metrics between healthy participants and those with type 2 diabetes acquired with multiparametric MRI.	To determine the range of body composition and multi-organ metrics (liver, pancreas, aorta, heart, kidney, lungs and spleen) in healthy participants and in those with type 2 diabetes assessed using multiparametric MRI.	24 months

Contacts/Locations Module

Condition Browse Module