Evaluation of Antithrombin Deficiency in Patients of Intensive Care Unit Placed on Extracorporeal Membrane Oxygenation

Evaluation of Antithrombin Deficiency in Patients of Intensive Care Unit Placed on Extracorporeal Membrane Oxygenation

Prospective, monocentric, non-interventional study in patients placed on extracorporeal membrane oxygenation (ECMO)

Our hypothesis is that ECMO initiation is responsible for a severe decrease of antithrombin level in a high proportion of patients who develop heparin resistance.

Inclusion Criteria:

• Any ICU patient of receiving veno-arterial extracorporeal membrane oxygenation
• Patients who have not expressed opposition to participate

Exclusion Criteria:

• Arterial thrombosis or progressive venous thrombosis
• Contraindication to heparin
• Constitutional deficiency in antithrombin
• Patient refusal
• Minor patient
• Protected major (safeguard justice, trusteeship and guardianship) and persons deprived of liberty