Sleep and Girls' Emotions Study

The Contribution of Stressful Life Events and Insufficient Sleep to Reward-Related Brain Function and Depression in Adolescent Girls

This study evaluates whether increasing sleep duration can increase neural and behavioral response to rewards and decrease depressive symptoms in 18- to 22-year-old women with insufficient sleep and depressive symptoms.

Inclusion Criteria:

• Insufficient sleep (total sleep time < 8 hours per night, with sleepiness scores ≥ 6 on the Epworth Sleepiness Scale OR ≥ 16 on the PROMIS Sleep Related Impairment Scale)
• Symptoms of depression (≥ 15 on the Center for Epidemiological Studies for Depression Scale)

Exclusion Criteria:

• Current insomnia, hypersomnia, sleep disordered breathing, sleep movement disorder, or circadian rhythm disorder
• History of head injury with loss of consciousness within the past two years
• History of head injury with loss of consciousness two or more years ago and meet criteria for post concussion syndrome
• Neurological disorder
• Use of psychiatric medications
• Current psychotic symptoms
• Active suicidal ideation
• Conditions that are contraindicated for MRI (e.g., ferromagnetic material in the body)
• Meet criteria for current substance use disorder with greater than mild severity