Autologous fat grafting, also known as lipofilling, is a surgical technique consisting in the processing and transfer of adipose tissue from one area in our organism (hips, thighs) to region which in need of reconstructive and aesthetic correction. The technique is frequently used after radical or conservative mammary surgery, aiming to achieve better aesthetic results, reduce pain induced by both surgery and radiotherapy. The scientific community was widely involved in the debate regarding the use of mesenchymal/stem cells in a patient with high risk of tumor progression due to their elevated proliferative profile. This study aims to retrospectively evaluate the oncological safety in the use of lipofilling in patients who underwent oncological and reconstructive treatment in our Institute.

Inclusion Criteria:

• female
• breast carcinoma (any histological type, carcinoma in situ included) treated with radical or conservative surgery
• group treated with lipofilling and group which didnt receive lipofilling
• timing: retrospective evaluation of cases form 2006 to 2016, with a minimum of two year follow up

Exclusion Criteria:

• neoplasie different from infiltrating and in sutu breast carcinoma
• in situ lobular carcinoma
• patients with breast carcinoma and metastasis
• lipofilling procedure used before the oncological treatment for breast carcinoma

Female patients with breast carcinoma (any histological type, carcinoma in situ included) and treated with radical or conservative surgery and lipofilling. Patients received a minimum of two year follow up.