Corneal edema is frequently found in clinical practice as a common sign of acute corneal disease due to different etiologies that cause an accumulation of extracellular fluid in the cornea. The present unicentric clinical trial aims to evaluate the efficacy and tolerance of an ophthalmic solution of hypertonic sodium chloride (NaCl 5%) without preservatives in participants suffering from symptomatic corneal edema.

Inclusion Criteria:

• Age over 18 years
• Clinical diagnosis of symptomatic corneal edema related to chronic epithelial, secondary to corneal dystrophies, controlled infectious and inflammatory pathologies and surgical trauma already resolved.
• No need for keratoplasty in the 6 months following the start of the study

Exclusion Criteria:.

• Visual acuity less than 1/20 in both eyes
• Corneal edema caused by the following acute etiologies: trauma, infection, inflammation or Stevens-Johnson syndrome.
• Glaucoma or uncontrolled hypertension.
• Known allergy to any of the ingredients of the product.