Intraprocedural Assessment of Ablation Margins Using Computed Tomography Co-registration in Primary Liver Tumor Treatment With Percutaneous Ablation

Intraprocedural Assessment of Ablation Margins Using Computed Tomography Co-registration in Primary Liver Tumor Treatment With Percutaneous Ablation

A pre- and postablation scan will be made intraprocedurally to investigate the feasibility of intraprocedural ablation verification assessment using coregistration software

Inclusion Criteria:

• Age 18 yrs or above
• HCC very early (0) or early stage (A) according to the BCLC staging system
• Either de novo or recurrent HCC (prior locoregional therapy is allowed in the study)
• Candidate for percutaneous thermal ablation as discussed in a multidisciplinary tumor board. Ablation as 'bridge-to-transplant' is allowed in the study

Exclusion Criteria:

• Estimated GFR <30 ml/min
• Morbid obesitas or any pulmonary condition that is a contraindication to prolonged apnea and high jet-ventilation
• Child Pugh C
• Portal vein tumor invasion
• Extrahepatic metastasis
• Uncorrectable coagulopathy
• Any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule
• Inability or unwillingness to give informed consent