Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
'This study aims to compare the effect of Metformin alone vs Metformin plus Apple Cider Vinegar in newly diagnosed Type 2 Diabetic Patients
Diabetes Mellitus is one of the oldest diseases known to men and has been treated with multiple agents,organic and with the current pharmacological advancement,with multiple synthetic drugs as well.
Metformin has been considered first line for the treatment of Type 2 Diabetes, however presents itself with a side effect profile of GI distress, Vitamin B12 deficiency,to name a few.
Vinegar has been used as therapeutic agent for centuries for multiple ailments including diabetes. This study aims to evaluate the combined effects of drug and natural therapy and compare it with conventional therapy.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 | Active Comparator | Intervention: Metformin Tablet oral 750 mg OD |
|
| Group 2 | Experimental | Intervention: Metformin 750 mg oral plus 2 tablespoons of apple cider vinegar OD |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Metformin Oral Tablet | Drug | A biguanide drug used as a first line therapy for Diabetes MellitusType 2 |
|
| Measure | Description | Time Frame |
|---|---|---|
| BMI (Anthropometric Measurement) | Body Mass Index: A measure of obesity calculated as weight in kilograms divided by height in meters square | 12 weeks |
| Measurement of Hemoglobin A1c | A blood test for Glycated Hemoglobin that represents a 2-3 month glycemic control | 12 weeks |
| Measurement of Fasting Blood Sugar | A blood test that involves the measurement of plasma glucose after 8 to 12 hours of fasting | 12 weeks |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Dr Momina Abid, MBBS,M Phil (ongoing) | Ziauddin University | Principal Investigator |
| Dr Zahida Memon, MBBS,M Phil,PhD | Ziauddin University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ziauddin University | Karachi | Sindh | 7500 | Pakistan |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D008687 | Metformin |
| D019342 | Acetic Acid |
| ID | Term |
|---|---|
| D001645 | Biguanides |
| D006146 | Guanidines |
| D000578 | Amidines |
| D009930 | Organic Chemicals |
| D000085 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Vinegar | Dietary Supplement | A common herbal/dietary supplement used for centuries as an anti bacterial, cleaning,cooking, anti diabetic agent, to name a few uses. |
|
| D004700 | Endocrine System Diseases |
| Acetates |
| D000144 | Acids, Acyclic |
| D002264 | Carboxylic Acids |
| D005232 | Fatty Acids, Volatile |
| D005227 | Fatty Acids |
| D008055 | Lipids |