This project addresses the role of lab markers around the time of central line placement in predicting risk of thrombosis in pediatric patients with central venous lines being placed. The project proposes an innovative way to predict higher risk of thrombosis in the pediatric population to give clinicians a valid tool to guide clinical practice for these patients.

Inclusion Criteria:

• Patients over 5 kg and less than 18 years of age.
• Patients having a central venous catheter or cardiac catheterization performed

Exclusion Criteria:

• prior history of thrombosis
• patients with hemophilia A or B

Pediatric patients having central venous line placement