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| Name | Class |
|---|---|
| Mohamed Wahid Elsayed Elsayed | UNKNOWN |
| Prof. Dr. Tamer Abdullah Helmy | UNKNOWN |
| Dr. Osama Saeed Hassan | UNKNOWN |
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Severe stroke remains an important cause of mortality and morbidity, despite advances in disease management, acute treatment and secondary measures. Among all post-stroke complications, pneumonia constitutes a major complication with a strong impact on morbidity and mortality. Research also showed that a reduction in respiratory muscle and abdominal muscle strength contributed to pulmonary and respiratory dysfunction following a stroke. Low respiratory muscle function decreases the efficacy of rehabilitation because it leads to exercise intolerance in stroke patients. Thus, special exercise programs are needed to improve the pulmonary function and respiratory muscle strength of stroke patients The aim of pulmonary rehabilitation program is to enhance respiratory muscle resistance during breathing, thereby improving respiratory function. Previous studies demonstrated that pulmonary rehabilitation programs improved respiratory functions in cardiac disease and chronic obstructive pulmonary disease patients
The study will be conducted on 80 adult patients with Acute Ischemic Stroke.
Inclusion criteria:
Exclusion criteria:
For every eligible patient the following data will be collected:
Grouping The patients will be randomized into 2 groups by conventional method of randomization where patients in group 1 (control group) will be selected in odd numbers and those in group 2 (patients receiving pulmonary rehabilitation program) will be selected in even numbers.
Stroke management Group 1: (Control group) 40 patients will receive Stroke management based on the guidelines of the American Heart Association/American Stroke Association.
Group 2: (Patients receiving pulmonary rehabilitation program) 40 patients will receive Stroke management based on the guidelines of the American Heart Association/American Stroke Association in addition to pulmonary rehabilitation program.
Enrolled patients will be prospectively followed up for:
Primary outcome:
• The diagnosis of pneumonia within the first 7 days after admission. (Diagnosis will be made according to modified criteria of the CDC
Secondary outcome:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patient | Active Comparator | 40 patients with acute stroke will receive Stroke management based on the guidelines of the American Heart Association/American Stroke Association.(20-22) in addition to pulmonary rehabilitation program. |
|
| control group | Placebo Comparator | 40 patients with acute stroke will receive Stroke management based on the guidelines of the American Heart Association/American Stroke Association. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| pulmonary rehabilitation program | Other | The pulmonary rehabilitation program consisting of inspiratory muscle training, manual hyperinflation. chest wall mobilization, rib-cage compression, cough function training, postural drainage and secretion removal will be applied to patient group. The program will be conducted by physical therapists for 30-45 minutes daily during ICU stay. The exercise intensity will be increased gradually over the course. Each patient's performance during the exercise sessions will be recorded and reported regularly. |
| Measure | Description | Time Frame |
|---|---|---|
| Primary outcome: The diagnosis of pneumonia within the first 7 days after admission. | Diagnosis will be made according to modified criteria of the CDC | within the first 7 days after admission |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality rate | Modified Rankin Scale (mRS) at one month | In-hospital after 30 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rehab Abdelaal ELnemr | Recruiting | Alexandria | 123456 | Egypt |
may be after finishing patient collection
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |