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Predicting the risk of stroke remains a challenge in the management of transient ischemic attack (TIA). In addition to clinical variables, morphological features such as the presence of a diffusion weighted sequence (DWI) lesion and carotid stenosis of at least 50% improve risk stratification and are considered in the literature. score ABCD3-I1. Several studies have shown that brain microhemorrhages are associated with the risk of early stroke in patients with TIA. Data on white matter hypersignals on the T2-weighted sequence or FLAIR (FLuid Attenuated Inversion Recovery) are more conflicting. The global microangiopathic load, including the gaps, the hypersignals of the white matter, the perivascular spaces visible on MRI in the basal ganglia, especially when they are very numerous (> 20) and the gaps, have recently been described as being associated with stroke risk within 2 to 3 years of TIA or ischemic stroke. To date, the predictive value of global microangiopathic burden on early stroke risk in the course of TIA is not known.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diagnosis of AIT | Patients in the neurovascular unit of the Neurological Hospital of Lyon between 01/01/2016 and 30/12/2017 with a probable diagnosis of AIT and having an MRI within 7 days of TIA. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| microangiopathic burden | Other | to determine the value of the global microangiopathic burden on the prediction of early stroke risk in a homogeneous cohort of TIA. |
|
| Measure | Description | Time Frame |
|---|---|---|
| stroke recurrence within 90 days, | The stroke recurrence within 90 days is determined via a clinical consultation or telephone call to the patient with a structured questionnaire. | 90 days |
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Inclusion Criteria:
Exclusion Criteria:
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All patients in the neurovascular unit of the Neurological Hospital of Lyon between 01/01/2016 and 30/12/2017 with a probable diagnosis of TIA and having an MRI within 7 days of the TIA.
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| Name | Affiliation | Role |
|---|---|---|
| Norbert NIGHOGHOSSIAN | Hospices Civils de Lyon | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospices Civils de Lyon | Bron | 69677 | France |
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