Prevalence and Risk Factor of NP in Women With LUTS

Prevalence and Risk Factors of Nocturnal Polyuria in Women With Lower Urinary Tracts Symptoms Based on Bladder Diary

The knowledge of prevalence and risk factors of nocturnal polyuria might be important for the treatment of women with lower urinary tract symptoms (LUTS). Thus, our aim is to describe the prevalence and risk factors of nocturnal polyuria in women with LUTS.

Between September 2010 and January 2019, all women with LUTS visiting urogynecological department of a medical center for urodynamic evaluation were reviewed. Nocturnal polyuria was defined when the proportion of night-time voided volume over 24-hour voided volume was greater than 33% for ≥65 year-old women, and when the proportion of night-time voided volume over 24-hour voided volume was greater than 20% for <65 year-old women. Backward stepwise multivariable logistic regression analysis was performed using all statistical variables in the univariate logistic regression analysis. P < 0.05 was considered as statistical significant.

Inclusion Criteria:

• Women with lower urinary tract symptoms
• Complete a 3-day bladder diary

Exclusion Criteria:

• <20 y/o or > 85 y/o
• Regular urethral catheterization or intermittent self-catheterization
• Urinary tract infection or chronic inflammation in the previous 2 weeks
• Bladder calculus
• Neurogenic bladder due to radical hysterectomy or injury of the central nervous system
• History of pelvic radiotherapy or a preexisting malignant pelvic tumor.