Unemployment is particularly common among women with multiple sclerosis (MS). This study uses a vocational rehabilitation program involving neuropsychological testing as an intervention. The use of in-person feedback and case management following neuropsychological testing is compared to phone feedback only. Adherence to treatment and employment outcomes will be evaluated over three years.

Employed women at a tertiary-care MS center were screened for common issues impacting work productivity (fatigue, cognitive dysfunction, and depression). Women who met screening criteria were randomized to one of two treatment groups: either neuropsychological testing and phone feedback to review findings and tailored recommendations (standard-care treatment); or neuropsychological testing, in-person feedback, and two calls from a care-coordinator (experimental treatment). Adherence to recommendations and employment status at one year are evaluated. Follow-up periods also occur at year two and year three.

Inclusion Criteria:

• Female sex
• Age between 18 and 64
• Employed at least 20 hours per week
• Confirmed diagnosis of MS

Exclusion Criteria:

• Experiencing an MS exacerbation
• Endorsing suicidal ideation or intent
• Pregnant
• Severe psychiatric disorder
• History of traumatic brain injury
• Dementia
• Major neurological illness other than MS

Study targeted females

Participants were informed that they would receive feedback but were not told whether it would be in person or by phone until after randomization. Participants were not informed that only one group received case management calls.