A Pilot Study of a Strategy and Computer-based Intervention to Enhance Daily Cognitive Functioning After Stroke

A Pilot Study of a Strategy and Computer-based Intervention to Enhance Daily Cognitive Functioning After Stroke

This is an initial pilot study to test feasibility, participant engagement and satisfaction, and clinical and neurobiological target engagement of a behavioral treatment called "ASCEND" that combines computer-based cognitive training and coaching of cognitive strategies to improve daily cognitive functioning in individuals with stroke.

Inclusion Criteria:

• History of first-time stroke, minimum of 6 months prior to enrollment
• English speaking
• Ability to comprehend sufficiently to participate in the treatment.
• Subjective or objective evidence of mild cognitive impairment
• Willingness to participate in full study duration
• Has computer that meets specification for the training program software.
• Physically able to operate a computer keyboard and mouse.
• Not concurrently receiving other cognitive rehabilitation services
• Cognitively able to perform basic self-care activities (e.g., dressing, grooming, eating).

Exclusion Criteria:

• History of neurologic disease other than stroke
• History of severe mental illness or substance use disorder, or current major depressive episode.
• History of dementia or dependence in basic self-care activities due to cognitive deficits
• Contraindications to MRI