Incremental Cost-Utility Study on Prehabilitation Among Older Patients With Colorectal Cancer Undergoing Surgery

Incremental Cost-utility Study on Prehabilitation for Colon Cancer Surgery in Older Patients

A prospective multicenter observational cost-utility study following older or high-risk patients with colorectal cancer with and without prehabilitation before surgery.

This study will answer the question whether prehabilitation is cost-effective in colorectal cancer surgery among individual patients aged 70 years and above or patients with an American Society of Anesthesiologists (ASA) score of III. We also aim to identify factors facilitating or impairing implementation of prehabilitation such that it is cost-effective.

Inclusion Criteria:

• Age ≥ 70 years or American Society of Anesthesiologists (ASA) score of III
• Scheduled for colorectal cancer surgery

Exclusion Criteria:

• Metastatic disease known preoperatively
• ASA IV score or higher
• Paralytic or immobilized patients (not capable to perform exercise)
• Prior use of neoadjuvant therapy for the same indication
• Not able or willing to provide written informed consent