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The study aims to investigate the characteristics of subjects with hypertension at onset among a cohort of apparently healthy subjects, with overweight or obesity (BMI ≥ 25 Kg / m2), and free of any drug treatment at the baseline. The evaluation includes anthropometric (weight, height, BMI, waist circumference), haematochemical (hormones, metabolic and routine) parameters and the screening for hypertension with ABPM. The diagnosis of hypertension is made in accordance with the 2017 guidelines of the American College of Cardiology / American Heart Association ACC / AHA.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observational study | Other | Observational and prospective study |
| Measure | Description | Time Frame |
|---|---|---|
| Insulin | Insulin (mIU/L) concentration in serum | At baseline |
| Potassium | Potassium (mmol/L) concentration in serum | At baseline |
| Sodium | Sodium (mEq/L) concentration in serum | At baseline |
| eGFR (estimated glomerular filtration rate) | eGFR (ml/min/1.73 mq) | At baseline |
| Creatinin | Creatinin (mg/dl) concentration in serum | At baseline |
| Uric acid | Uric acid (mg/dL) concentration in serum | At baseline |
| Total cholesterol | Total cholesterol (mg/dL) concentrations in serum | At baseline |
| Thyroid hormones (FT3, FT4) | FT3 (pg/mL), FT4 (pg/mL) concentration in serum | At baseline |
| HDL cholesterol | HDL cholesterol (mg/dL) concentrations in serum |
| Measure | Description | Time Frame |
|---|---|---|
| BMI | BMI (kg/m^2) | At baseline |
| Height | Height in meters | At baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who came to the Outpatient Clinic of Nutrition at the National Institute of Gastroenterology "S. de Bellis," Research Hospital, Castellana Grotte, Italy.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Institute of Gastroenterology IRCCS S. de Bellis | Castellana Grotte | Bari | 70013 | Italy |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
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| ID | Term |
|---|---|
| D019370 | Observation |
| ID | Term |
|---|---|
| D008722 | Methods |
| D008919 | Investigative Techniques |
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| At baseline |
| LDL cholesterol | LDL cholesterol (mg/dL) concentrations in serum | At baseline |
| Triglycerides | Triglycerides (mg/dL) concentrations in serum | At baseline |
| TSH | TSH (mU/L) concentration in serum | At baseline |
| Weight |
Weight in kilograms |
| At baseline |
| D009748 |
| Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |