Removal of mtDNA in Plasma by Continous Venovenous Hemofiltration in Sepsis

Removal of mtDNA in Plasma by Continous Venovenous Hemofiltration in Sepsis

The plasma level of mtDNA in sepsis is affected by continous venovenous hemofiltation（CVVH）

Continous renal replacement therapy （CRRT）has become routine for patients with chronic renal failure ，AKI，fliud overload as well as oliguria in ICU .In clinical patients ，continous venovenous hemofoiltration （CVVH）is actually the method of chioce for CRRT in critically ill and hemodynamic instable patients .CVVH has significant beneficial effects on removing inflammatory cytokines ，improving oxygen index，increasing cardiac index and regulating immune dysfuntion .

Inclusion Criteria:

Adult septic patients undergoing CRRT

Exclusion Criteria:

1. Missing vists
2. transplatation
3. cancer
4. aquired immunodeficiency syndrome