A Study of Lasmiditan in Healthy Chinese Participants

Safety, Tolerability, and Pharmacokinetics of Lasmiditan in Healthy Chinese Subjects

This is a study of lasmiditan in healthy Chinese participants. The purposes are:

• To evaluate the safety of lasmiditan
• To learn more about how the body processes lasmiditan

The study will last up to 50 days for each participant.

Inclusion Criteria:

• Are overtly healthy Chinese (all 4 biological grandparents and both biological parents to be of Chinese origin) males or females, as determined by medical history and physical examination
• Have a body mass index (BMI) of 18.0 to 32.0 kilograms per square meter, inclusive
• Are able and willing to give signed informed consent

Exclusion Criteria:

• Have known allergies to lasmiditan, related compounds or any components of the formulation
• Have an abnormal blood pressure and/or pulse rate as determined clinically significant by the investigator
• Have a history of, show evidence of, or are undergoing treatment for significant active neuropsychiatric disease (for example, manic depressive illness, schizophrenia, depression)
• Have a history of central nervous system (CNS) conditions such as strokes, transient ischemic attack, significant head trauma, CNS infections, migraines, brain surgery, or any other neurological conditions that, in the opinion of the investigator, increases the risk of participating in the study
• Regularly use known drugs of abuse and/or show positive findings on drug screening