Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
A ketogenic diet (KD) is a nutritional approach, usually adopted for weight loss, that restricts daily carbohydrates under 30 g/day. KD showed contradictory results on sport performance, whilst no data are available on team sports. The investigators will investigate the influence of a KD on different parameters in soccer players
Sixteen semi-professional soccer players will be randomly assigned to a ketogenic diet (KD n=8) or to a western diet (WD n=8). Diets contain the same amount of protein (1.8g/Kg body weight/day). Body weight and body composition will be measured by dual energy x-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA). Resting energy expenditure (REE), respiratory exchange ratio (RER), cross sectional area (CSA) and isometric muscle strength of quadriceps, counter movement jump (CMJ) and yoyo intermittent recovery test will be measured.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ketogenic diet | Experimental | Ketogenic diet: less than 30 g/day of carbohydrate. Subjects can eat beef, veal, poultry, fish, raw and cooked vegetables without restriction, cold cuts such as dried beef, eggs and seasoned cheese (parmesan), ketogenic pasta (selected with a ketogenic ratio of 4:1), fruits with the lowest glycemic index (blueberry, raspberry), raw nuts and seeds, ghee butter, plant oils and fats from avocado, coconut and olives |
|
| Western diet | Active Comparator | The western diet (WD) is composed mainly of whole cereals (spelt, rye, oat) and pseudo-cereals (buckwheat, quinoa, amaranth), whole grain pasta, potatoes, meet, fish, vegetables, fruit, legumes, olive oil, milk and red wine (at most 1 glass per day). It ensure a constant energy and macronutrient balance: protein 1.8g x Kg-1 x body weight-1 x day-1, (30%), fats 20-25% and carbohydrate 50-55%. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Western diet | Other | Subjects in this intervention will follow a normal western diet |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Fat body mass | Body composition with DEXA: we measure body fat mass in grams. | 4 weeks |
| lean body mass | Body composition with DEXA: we measure lean body mass in grams. | 4 weeks |
| Visceral Adipose tissue (VAT) | Body composition with DEXA: VAT in grams | 4 weeks |
| Total body water | We will use a BIA to calculate totally body water and intracellular and extracellular water in liters | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| resting energy expenditure (REE) | Measured through gas analyzer in ml/02/kg min | 4 weeks |
| respiratory ratio (RR) | Measured through gas analyses (ratio between CO2 and O2) |
Not provided
Inclusion Criteria
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Antonio Paoli, MD | University of Padova | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nutrition and Exercise Lab, DSB, University of Padova | Padova | 35131 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27803969 | Background | Rubini A, Bosco G, Lodi A, Cenci L, Parmagnani A, Grimaldi K, Zhongjin Y, Paoli A. Erratum to: Effects of Twenty Days of the Ketogenic Diet on Metabolic and Respiratory Parameters in Healthy Subjects. Lung. 2017 Feb;195(1):155. doi: 10.1007/s00408-016-9958-0. No abstract available. | |
| 25906427 | Background | Paoli A, Bianco A, Grimaldi KA. The Ketogenic Diet and Sport: A Possible Marriage? Exerc Sport Sci Rev. 2015 Jul;43(3):153-62. doi: 10.1249/JES.0000000000000050. |
Not provided
Not provided
Raw data of outcomes on request
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D066273 | Diet, Western |
| D055423 | Diet, Ketogenic |
| ID | Term |
|---|---|
| D004032 | Diet |
| D009747 | Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
Not provided
Not provided
It is single blind, parallel arms study
Not provided
Not provided
Treatment and control were masked with A and B
| ketogenic diet |
| Other |
Subjects in this group will follow a low carbohydrate ketogenic diet |
|
| 4 weeks |
| specific performance | Yoyo intermittent recovery test level 1: in seconds | 4 weeks |
| lower limb power | squat jump test: height of the jump in cm | 4 weeks |
| quadriceps muscle area | muscle area measured in cm2 through ultrasound | 4 weeks |
| quadriceps muscle thickness | muscle thickness measured cm through ultrasound | 4 weeks |
| quadriceps strength | isometric contraction measured in N, the normalized per muscle area (N x cm2) | 4 weeks |
| quadriceps strength per area | the strength of isometric contraction (outcome 10) normalized per muscle area (Outcome 7). Expressed as (N x cm2) | 4 weeks |
| 22835211 | Background | Paoli A, Grimaldi K, D'Agostino D, Cenci L, Moro T, Bianco A, Palma A. Ketogenic diet does not affect strength performance in elite artistic gymnasts. J Int Soc Sports Nutr. 2012 Jul 26;9(1):34. doi: 10.1186/1550-2783-9-34. |
| 34530857 | Derived | Antonio Paoli A, Mancin L, Caprio M, Monti E, Narici MV, Cenci L, Piccini F, Pincella M, Grigoletto D, Marcolin G. Effects of 30 days of ketogenic diet on body composition, muscle strength, muscle area, metabolism, and performance in semi-professional soccer players. J Int Soc Sports Nutr. 2021 Sep 16;18(1):62. doi: 10.1186/s12970-021-00459-9. |
| D050528 | Diet, Carbohydrate-Restricted |
| D004035 | Diet Therapy |
| D044623 | Nutrition Therapy |
| D013812 | Therapeutics |