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Study Objectives/Specific Aims Overall Goal: To compare between transseptal approach and the conventional left atrial approach for mitral valve procedures.
Mitral valve diseases are considered among the most prevalent valvular heart diseases that necessitate surgical intervention.
as the Modern international guidelines substantially recommend mitral valve repair whenever possible there is significant decrease in mitral valve replacement rates.
Cardiothoracic surgeons have to face the problem of Making a decision regarding mitral valve repair, reconstruction or replacement which requires excellent valve exposure for precise anatomical definition and manipulation taking in mind cases with specific anatomical challenges.
Since the beginning of modern cardiac surgery only two basic approaches to the mitral valve have been described by Effler who wrote in 1958 " the actual entry into the left atrium may be accomplished in either of two ways : through the Fossa Ovalis by way of the right atrium or through the posterior interatrial groove " Nowadays median sternotomy is still the most commonly used incision for mitral valve surgery which allows the best exposure for the valve through transseptal incision or through Sandergaard's groove.
Although the latter approach is the preferred method for most surgeons the transseptal approach has been revisited in more recent years in various forms by those seeking better exposure of mitral valve especially in cases with difficult anatomy.
In this paper we try to compare the transseptal approach with the conventional left atrial approach for mitral valve procedures to review previous literatures' results and to clarify the effect of using each of the two approaches in preoperative ,intra and postoperative course .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group A | underwent mitral valve surgery through transseptal approach. |
| |
| group B | underwent mitral valve surgery through conventional left atrial approach. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transseptal approach. | Procedure | surgical approach to the mitral valve through the Fossa Ovalis by way of the right atrium. |
|
| Measure | Description | Time Frame |
|---|---|---|
| ischemic time | period of time from applying the aortic cross clamp till its removal in open heart surgeries during which there is no blood flow in the coronary arteries and the heart is ischemic. | intraoperative registration. |
| whole operation time. | period of time from skin incision to skin closure in open heart surgery. | intraoperative registration. |
| re-operation | re exploration through the same incision site to stop bleeding. | with in the first 24 hrs post operative. |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative arrhythmias. | newly arising tachy or bradyarrhythmia | within the first week post operative. |
| Hospital stay. | time of hospital admission postoperative. |
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Inclusion Criteria:
Exclusion Criteria:
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all patients who presented to Cardiothoracic Surgery Department, Assiut University Hospital and who meet the listed inclusion from 2016 to 2019 within the range of 100 eligible case.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Beshoy Allam, master | Contact | +201009471147 | beshoui011145@med.au.edu.eg | |
| Ahmed ELminshawy, prof. dr. | Contact | 01148185466 | aelminshawy@aun.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Mahmoud Thabet, dr. | general surgery department, AssiutU | Study Director |
| Mohamed Mahmoud, dr. | cardiothoracic department, AssiutU | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26985207 | Background | Rezahosseini O, Rezaei M, Ahmadi Tafti SH, Jalali A, Bina P, Ghiasi A, Karimi A, Abbasi K, Shirzad M, Davoodi S, Salehi Omran A. Transseptal Approach versus Left Atrial Approach to Mitral Valve: A Propensity Score Matching Study. J Tehran Heart Cent. 2015 Oct 27;10(4):188-93. | |
| 28757798 | Background | van der Merwe J, Casselman F. Mitral Valve Replacement-Current and Future Perspectives. Open J Cardiovasc Surg. 2017 Jul 13;9:1179065217719023. doi: 10.1177/1179065217719023. eCollection 2017. |
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| up to three months |
| 24414707 | Background | Doty JR, Caine WT. Mitral valve replacement and tricuspid valve repair through a transseptal approach for double-valve endocarditis. Multimed Man Cardiothorac Surg. 2012 Jan 1;2012:mms003. doi: 10.1093/mmcts/mms003. |
| 16928494 | Background | Nienaber JJ, Glower DD. Minitransseptal versus left atrial approach to the mitral valve: a comparison of outcomes. Ann Thorac Surg. 2006 Sep;82(3):834-9; discussion 839. doi: 10.1016/j.athoracsur.2006.04.014. |
| 9339510 | Background | Santibanez Escobar F, Serrano Gallardo G, Ramirez Marroquin S, Lopez Soriano F, Barragan Garcia R. The transseptal approach for mitral valve replacement revisited. Tex Heart Inst J. 1997;24(3):209-14. |