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| Name | Class |
|---|---|
| National Institute for Medical Research, Tanzania | OTHER_GOV |
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HIV antiretroviral therapy (ART) has the potential to dramatically decrease HIV transmission worldwide. In Tanzania, HIV prevalence is ~5%, with 1.6 million people living with HIV/AIDS; it is the leading cause of hospitalization and death among Tanzanian adults. However, less than 50% of HIV-infected Tanzanian adults know their status.Successful implementation of community-based services requires an understanding of the social and cultural context that influence community engagement with HIV services. Specifically, many HIV endemic regions are also medically pluralistic communities, where multiple explanatory frameworks for health and disease co-exist. In these areas, HIV testing and ART clinical care do not occur in isolation; traditional healers are commonly utilized instead of or concurrently with biomedical services. Therefore, the success of decentralized, community-based HIV services must be founded upon a thorough understanding of medical pluralism, and engagement with traditional healers as stakeholders in community health.
This study will investigate the feasibility of involving traditional healers in HIV testing, and pilot an intervention to expand HIV testing within communities that use traditional medicine in Mwanza, Tanzania.
This study has two specific aims.
Specific Aim 1:
Tailor a point of care HIV testing intervention for delivery in northwestern Tanzania, using data from 1) qualitative interviews and 2) community engagement strategies. Interviews with traditional healers, traditional and biomedical clients, and HIV clinic staff will illustrate local variables impacting HIV testing engagement. A community advisory board with stakeholder members will guide program implementation, tailoring protocols to maximize uptake.
Specific Aim 2:
Conduct a cluster-randomized pilot of the HIV testing intervention. This pilot will offer HIV testing at five traditional healer practice sites, compared with a control group of five healers providing education on community HIV resources..
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Point-of-care HIV testing (intervention) | Experimental | Participants will be offered voluntary point-of-care HIV testing during a traditional healer visit. |
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| Education on community HIV resources (control) | Active Comparator | Participants will be offered education regarding HIV testing and community resources during a traditional healer visit. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Point-of-care HIV testing | Diagnostic Test | Participants will undergo an HIV 1/2 antibody point of care test (Oraquick) and receive pre- and post-test counselling.Participants with positive tests will be referred to the HIV clinic for Western Blot confirmation, and linkage to care. |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of HIV testing | Rate of HIV testing among clients of traditional healers who were offered point-of-care HIV testing, as compared to clients who were offered education regarding community HIV resources. | Within 3 months following visit |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of new HIV diagnosis | Rate of new HIV diagnosis among clients of traditional healers who were offered point-of-care HIV testing, as compared to clients who were offered education regarding community HIV resources. | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Linkage to HIV care at 3 months post enrollment | Rate of successful care linkage for participants with a new HIV diagnosis who received point-of-care HIV testing as compared to participants who received education regarding community HIV resources.Linkage to care will be defined as accessing outpatient care or treatment such as antiretroviral therapy (ART). | 3 months |
Inclusion Criteria:
Inclusion specific to point-of-care HIV testing intervention:
Exclusion Criteria:
Exclusion specific to point-of-care HIV testing intervention:
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| Name | Affiliation | Role |
|---|---|---|
| Radhika Sundararajan, PhD, MD | Weill Medical College of Cornell University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Institute for Medical Research | Mwanza | Tanzania |
Individual participant data that underlie the results reported in this article, after deidentification (text, tables, figures, and appendices) will be made available.
Data will be available beginning 3 months and ending 5 years following article publication.
Requests should be directed to ras9199@med.cornell.edu .
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| ID | Term |
|---|---|
| D015438 | Health Behavior |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| HIV testing education | Behavioral | Participants will be provided with education on community based HIV resources. |
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