PTNS on Urinary and Global Quality of Life in MS Patients

Impact of Percutaneous Posterior Tibial Nerve Stimulation on Urinary and Global Quality of Life in Multiple Sclerosis Patients

This is a single-centered, prospective, longitudinal, observational cohort study of patients with MS who suffer from lower urinary tract symptoms (LUTS) and are refractory to two prior treatment modalities who have elected to pursue PTNS therapy for LUTS.

Inclusion Criteria:

• Diagnosis of Multiple Sclerosis
• Lower urinary tract symptoms (urinary frequency, urgency and/or incontinence)
• Failed prior first and second line therapy (behavioral and pharmacotherapy)
• Electing for Posterior Tibial Nerve Stimulation therapy for urinary symptoms
• Patients performing Intermittent Catheterization are Eligible

Exclusion Criteria:

• Indwelling catheters (urethral or suprapubic)
• Currently pregnant or planning pregnancy
• Unable to attend weekly office visits for PTNS
• Urodynamic findings of bladder outlet obstruction

History of:

bladder reconstruction (augmentation cystoplasty, catheterizable channel) cystectomy bladder stones pacemaker or defibrillator malignancy of bladder sacral neuromodulation intravesical injection of onabotulinum toxin within 9 months