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| ID | Type | Description | Link |
|---|---|---|---|
| NCI-2019-04530 | Registry Identifier | CTRP (Clinical Trial Reporting Program) | |
| I 68718 | Other Identifier | Roswell Park Cancer Institute | |
| P01CA217806 | U.S. NIH Grant/Contract | View source | |
| P30CA016056 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Cancer Institute (NCI) | NIH |
| University of Minnesota | OTHER |
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This trial examines the effects of filter ventilation on sensory response, smoking topography, and inhalation in current every day cigarette smokers. The physical design features of cigarettes directly impact their appeal by influencing cognitive and sensory perceptions. The introduction of a now common design feature, filter ventilation, has led to greater public harm than benefit because of the potential for greater toxicity while enhancing product appeal among smokers. Ventilated cigarettes dilute smoke, which promotes perceptions of ?smoothness? and therefore lower health risk, contributing to the overall appeal of these products. The purpose of this study is to assess whether removing ventilation from cigarette filters lowers cigarette product appeal among smokers.
PRIMARY OBJECTIVES:
I. To assess the link between marketing proxies for filter ventilation (product descriptors, packaging) and risk beliefs.
OUTLINE:
Patients smoke 5 cigarettes separated by 30 minute washout periods. Between 48 hours and 1 week later, patients smoke another 5 cigarettes separated by 30 minute washout period with CReSSMicro topography measurement device and BioRadio device for recording inhalation patterns.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Observational (smoke cigarettes) | Patients smoke 5 cigarettes separated by 30 minute washout periods. Between 48 hours and 1 week later, patients smoke another 5 cigarettes separated by 30 minute washout period with CReSSMicro topography measurement device and BioRadio device for recording inhalation patterns. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Medical Device | Device | Smoke cigarettes with CReSSMicro topography measurement device and BioRadio device |
|
| Measure | Description | Time Frame |
|---|---|---|
| Modified Cigarette Evaluation Questionnaire | Scored using an established algorithm. This results in 3 subscales (psychological reward, relief, reward) and 2 single items (aversion, respiratory sensation). | Up to 210 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Carbon monoxide (CO) boost | Defined as the difference between pre-smoking exhaled CO and postsmoking exhaled CO. | Up to 210 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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Patients currently smoking daily at least 5 cigarettes per day for at least one year
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| Name | Affiliation | Role |
|---|---|---|
| Richard J O'Connor | Roswell Park Cancer Institute | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States |
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| Questionnaire Administration | Other | Ancillary studies |
|
| Tobacco Smoking | Behavioral | Smoke cigarettes |
|
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| ID | Term |
|---|---|
| D004864 | Equipment and Supplies |
| D000074602 | Smoking Devices |
| ID | Term |
|---|---|
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |
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