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The current RCT is designed to:
To accomplish these goals investigators will conduct a double-blind, placebo-controlled, RCT, applying the group mSMT to a sample of 60 participants with moderate to severe TBI (30 treatment; 30 control).
Outcome measures will assess objective memory abilities, everyday memory abilities and patterns of cerebral activation during learning. A long-term follow-up assessment will be conducted, designed to measure the impact of the mSMT 3 months following treatment completion. Alternate forms will be utilized wherever available.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group memory retraining | Experimental | Experimental group will be receiving memory retraining exercises via lap top twice a week for 5 weeks. Four people in a group. |
|
| Placebo | Placebo Comparator | Experimental group will be receiving memory retraining exercises via lap top twice a week for 5 weeks. Four people in a group. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Group Memory retraining exercises | Behavioral | Experimental group will be receiving memory retraining exercises via lap top twice a week for 5 weeks. Four people in a group. |
|
| Measure | Description | Time Frame |
|---|---|---|
| California Verbal Learning Test | Change on scores on memory tests will be assessed using the California Verbal Learning Test | Change will be assessed. Scales will be administered at 3 time points;pretreatment immediately following 5 months later |
| The Traumatic Brain Injury-Quality of Life Scale | Self-reports of emotional functioning, memory functioning and quality of life on The Traumatic Brain Injury-Quality of Life Scale, which measures these constructs. DVs will be change on the Depression subscale (range: 0-40; lower score is better) and Cognition scale (range: 0-40; higher score is better). | Change will be assessed. Scales will be administered at 3 time points;pretreatment immediately following 5 months later |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Richard Green, PhD | Kessler Foundation | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kessler Foundation | West Orange | New Jersey | 07052 | United States |
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| ID | Term |
|---|---|
| D000070642 | Brain Injuries, Traumatic |
| ID | Term |
|---|---|
| D001930 | Brain Injuries |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Placebo controlled group memory exercise training | Behavioral | Placebo group will be receiving memory retraining exercises via lap top twice a week for 5 weeks. Four people in a group. |
|
| D006259 |
| Craniocerebral Trauma |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |