Agitation in the intensive care unit is motor hyperactivity. It is frequent (b/w 30% to 70%) and has multiple causes: pain, medical reason, delirium, medication, etc. It can be a source of complication, for the patient, and equipment pullout. International recommendations state that the agitation should be taken care of with standardized protocols to improve patient care.

Data regarding patient characteristics and evaluation criterion will be collected automatically with the unit software (CCC, General Electrics) in specific file.

Care and health teams enter the data systematically following the usual protocol.

First Step :

Follow-up and collection of data of patients included. Agitation evaluation with RASS scale, pain evaluation with BPS or NPRS.

Second Step:

Team training to delirium evaluation scale (CAM-ICU) and to the use of care algorithm.

Third Step:

Follow-up and collection of data of patients included. Use of care algorithm by doctors, nurses and back up training nurse to ensure daily information to health professionals of the care unit.

Concomitant Step:

Post discharge from care unit medical appointment to evaluate anxiety symptoms (HAD scale) and quality of life (SF-12)

Inclusion Criteria:

• Patient presenting an agitation episode (RASS>1)
• Intensive care unit hospitalization
• Patient or next of kin if patient not able non opposed on participating to the study

Exclusion Criteria:

• Decision to limit life-sustaining therapy
• Brain damage
• Moribund patient
• Patient participating to another trial excluding observational studies
• The patient is pregnant or a lactating female
• Patient under tutorship or curatorship and liberty deprived

Patients admitted in the intensive care unit requiring and presenting a first episode of agitation.