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This study aims to evaluate the effect of individual reminiscence therapy (RT) on the global cognitive function of people with neurocognitive disorders attending social responses and to evaluate the ability of individually applied reminiscence therapy (RT) to improve overall cognitive function, memory, executive function, mood and quality of life (QoL) of elderly people with neurocognitive impairment attending social responses. It is proposed a multicenter study with an experimental design with randomized controlled repeated measures. Participants in the intervention group will hold two RT sessions per week for three months. Control group participants will maintain their treatment as usual.
Neurocognitive disorder is a major cause of disability among older people and its incidence is increasing due to an aging population. Neurocognitive disorders globally are estimated to affect 44.35 million people and it is expected that by the year 2050 the number of affected people globally will triple to 135.46 million.
The absence of effective pharmacological treatment that stops or slows down the development of the disease has aroused interest in non-pharmacological therapies as a complement to pharmacological treatment that may improve the quality of life of people with neurocognitive disorders. One of the most investigated and most traditional non-pharmacological therapy in this field is Reminiscence Therapy (RT).
RT involves discussing past activities, events and experiences, usually with the help of triggers, such as photographs, household objects and other familiar items from the past, music… that is, any object or stimulus that serves to stimulate remembrance. In its application to dementia, RT is based on the fact that the memory impairment of people with dementia means that they are able to recall events from their past life, especially from childhood to early adulthood, but cannot remember more recent facts. It focuses on preserved memories and abilities, promotes communication, and enables the person to connect with his/her past and regain his/her sense of personal identity. Thus, RT can be understood as an intervention on the edge of those of cognitive orientation and emotion-centered, with potential interactive effects on autobiographical memory and psychological well-being.
The investigators can distinguish at least two RT approaches. The first one is the "life review" where participants are guided through meaningful experiences from their biography trying to make sense of their life. This type of RT is more structured and is usually conducted in an individual format. It may imply the construction of "life books". This approach is considered to have an integrative function aimed at achieving a sense of validation, coherence and reconciliation with the person's past. Another approach is the simple reminiscence which involves the stimulation of autobiographical memory during conversations about specific themes of the past (such as holidays, food and drinks, work…) using stimuli that trigger memories. It has been described as an unstructured narrative of autobiographical memories. This reminiscence format can be conducted both individually and in groups and promotes communication between participants who share their memories and stories.
In any of the TR formats it is essential to introduce triggering stimuli (photographs, music, antique objects…) to aid in recall. These triggers may be generic, reflecting common experiences in the lives of people relevant to their age group (for example a textbook may serve to recall the experience during their school stage), or specific, with stimuli related to the individual's own experiences (for example photographs of an important life event such as your wedding day or a trip during your youth).
Regarding the effectiveness of RT, according to a recent Cochrane review, there is some evidence for its positive effects on cognition, QoL, communication, and possibly mood of people with dementia, although benefits are small. Despite the distinction between the two different approaches to RT (simple reminiscence vs. life review), the modality of therapy does not seem to be as important for positive effects as the individual or group format of the sessions and the context in which the intervention is administered (people who live in the community or people who are institutionalized).
According to the results of one review study, RT seems to be able to generate a small benefit on cognitive function immediately after the intervention, although it usually does not persist after a follow-up period. Regarding the administration format, individual RT effects seems slightly superior on cognition both immediately and after a follow-up period. In any case, its effects appear to be comparable to those of other cognitive stimulation therapies.
As for the effect of RT on QoL, a life-review-based individual RT study showed an improvement in Qol-AD. Effects with a group format do not seem consistent, showing little or no effect on QoL, although the key factor may be the application context (community vs. institution), with better results of group RT in institutionalized patients.
Group RT was associated with an effect on communication both after the intervention and at follow-up. This effect was not replicated in individual RT, with uncertain results.
Finally, despite evidence of the effect of RT on mood of older people without dementia, in the case of people with dementia only a small effect on mood was found for those participants. in individual RT.
Therefore, this research proposal aims to evaluate the ability of individual RT using a simple reminiscence format to improve the overall cognitive function, memory, executive function, mood and quality of life (QoL) of people with neurocognitive disorder attending social responses for the elderly.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention Group | Experimental | Participants who meet the inclusion criteria will be randomly assigned to the intervention group receiving Reminiscence Therapy or to a control group receiving treatment as usual. Participants in the intervention group will participate in two Reminiscence Therapy sessions per week for 3 months besides their treatment as usual. The sessions will be based on the Book of Past and Present and they will follow the same protocol in every participant institution. |
|
| Control Group | No Intervention | Participants assigned to the control group will maintain their usual treatment in the institution, participating in the activities previously assigned to their individual care plan. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Reminiscence Therapy | Other | Intervention group will receive two Reminiscence Therapy sessions per week for 3 months. Reminiscence therapy sessions will last approximately 50 minutes and will be developed according to the following structure:
|
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive functioning evaluated through Mini-Mental State Examination | Significant statistic improvement in the participant's test scores between pre-intervention assessment and post-intervention assessment. Mini-Mental State Examination is a brief cognitive screening test. Scores range between 0 - 30 points. Higher scores indicate better cognitive function. | Pre and post-intervention (3 months) |
| Measure | Description | Time Frame |
|---|---|---|
| Memory funtion evaluated through Memory Alteration Test | Significant statistic improvement in the participant's test scores between pre-intervention assessment and post-intervention assessment. Memory Alteration Test is an easy and fast instrument that assesses five memory domains: orientation in time, short term memory, semantic memory, free recall and recall with clues. Scores range between 0 - 50 points. Higher scores indicate better memory. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Susana I Justo Henriques, PhD | Cediara and University of de Santiago de Compostela | Principal Investigator |
| Enrique Pérez Sáez, PhD | CRE Alzheimer and University of Salamanca | Principal Investigator |
| João L Alves Apóstolo, PhD | Nursing School of Coimbra | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cediara - Assoc. Sol. Social de Ribeira de Fráguas | Albergaria-a-Velha | Aveiro District | 3850-705 | Portugal | ||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21543189 | Background | Akanuma K, Meguro K, Meguro M, Sasaki E, Chiba K, Ishii H, Tanaka N. Improved social interaction and increased anterior cingulate metabolism after group reminiscence with reality orientation approach for vascular dementia. Psychiatry Res. 2011 Jun 30;192(3):183-7. doi: 10.1016/j.pscychresns.2010.11.012. Epub 2011 May 4. | |
| 26572551 |
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|
| Pre and post-intervention (3 months) |
| Executive functions evaluated through Frontal Assessment Battery | Significant statistic improvement in the participant's test scores between pre-intervention assessment and post-intervention assessment. Frontal Assessment Battery assesses executive functions such as abstract thinking, mental flexibility, motor programming, interference sensibility, inhibitory control and environmental independence. Scores range between 0 - 18 points. Higher scores indicate better cognitive function. | Pre and post-intervention (3 months) |
| Mood evaluated through Geriatric Depression Scale -15 | Significant statistic improvement in the participant's test scores between pre-intervention assessment and post-intervention assessment. Geriatric Depression Scale -15 is composed by 15 yes/no answer items and it has good psychometric characteristics to assess depression in older people. Scores range between 0 - 15 points. Higher scores indicate more severe depressive symptoms. | Pre and post-intervention (3 months) |
| Quality of life evaluated through Quality of Life - Alzheimer's Disease | Significant statistic improvement in the participant's test scores between pre-intervention assessment and post-intervention assessment. Quality of Life - Alzheimer's Disease is an instrument to assess quality of life in people diagnosed with dementia, gathering information from the patient and the caregiver. It is composed by 13 items regarding perception of health, mood, functional abilities, interpersonal relationships and hobbies, decision making ability and life in general. It has good psychometric characteristics and it's use has been recommended to evaluate psychossocial interventions. Scores range between 13 - 52 points. Higher scores indicate better quality of life. | Pre and post-intervention (3 months) |
| Rsocialform - Geriatria, Lda. |
| Mealhada |
| Aveiro District |
| 3050-387 |
| Portugal |
| Santa Casa Da Misericórdia de Ovar | Ovar | Aveiro District | 3880-225 | Portugal |
| Lar D. Pedro V | Praia da Vitória | Azores | 9760-458 | Portugal |
| Delicate Age Lda. | Portimão | Faro District | 8500-684 | Portugal |
| APARSIN - Assoc. Port. de Apoio e Reabilitação Sénior de Intervenção Neurológica | Elvas | Portalegre District | 7350 | Portugal |
| Santa Casa Da Misericordia de Almada - Centro São Lázaro | Almada | Setúbal District | 2800-119 | Portugal |
| Centro Social Vale Do Homem | Braga | 4730-263 | Portugal |
| Santa Casa Da Misericórdia de Vila Verde | Braga | 4730-416 | Portugal |
| Centro Zulmira Pereira Simões | Braga | 4750-650 | Portugal |
| Santa Casa Da Misericórdia de Castelo Branco | Castelo Branco | 6000-773 | Portugal |
| Santa Casa Da Misericórdia de Vila Velha de Ródão | Castelo Branco | 6030-230 | Portugal |
| Centro Social Paroquial Dornelas | Guarda | 3570-130 | Portugal |
| Primavida Residência Sénior Amor | Leiria | 2400-792 | Portugal |
| Santa Casa Da Misericórdia de Alcobaça | Leiria | 2460-009 | Portugal |
| Santa Casa Da Misericórdia Do Alvorge | Leiria | 3240-407 | Portugal |
| Associação Alzheimer Portugal | Lisbon | 1300-125 | Portugal |
| Irmãs Hospitaleiras - Casa de Saúde Da Idanha | Lisbon | 2605-077 | Portugal |
| Centro Social de Tolosa | Portalegre | 6050-501 | Portugal |
| Centro Social Paroquial Recarei | Porto | 4585-905 | Portugal |
| Associação de Solidariedade Social S. Tiago de Rebordões | Porto | Portugal |
| Santa Casa Da Misericordia de Coruche | Santarém | 2100-111 | Portugal |
| Santa Casa Da Misericórdia de Melgaço | Viana do Castelo | 4960-529 | Portugal |
| Santa Casa Da Misericórdia de Vouzela | Viseu | 3670-257 | Portugal |
| Pesqueiramiga- Associação de Solidariedade Social | Viseu | 5130-376 | Portugal |
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| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| D003704 | Dementia |
| D019965 | Neurocognitive Disorders |
| D003863 | Depression |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D001523 | Mental Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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