ICU-acquired Colonization and Infection Related to MDR in Immunocompromised Patients

Intensive Care Unit (ICU)-Acquired Colonization and Infection Related to Multidrug Resistant Bacteria (MDR) in Immunocompromised Patients

the number of immunocompromised patients hospitalized in the intensive care units (ICU) is increasing. They are at higher risk of colonization and/or infection with multi-resistant bacteria (MDR). However this risk is not well characterized. ICU acquired infections related to MDR are associated with increased morbidity and mortality. The aim of this study is to compare the incidence of ICU-acquired colonization and ICU-acquired infection related to MDR between immunocompromized and immunocompetent patients. The risk factors for ICU-acquired colonization and ICU-acquired infections, and their impact on outcome will also be evaluated and compared between immunocompromised and immunocompetent patients.

Inclusion Criteria:

• Expected ICU stay > 48 hours
• All patients (immunocompromised or immunocompetent).

Exclusion Criteria:

• Patients aged < 18 years
• Refusal to take part in the study
• ICU-stay < 48 hours
• Non availability of initial MDR or subsequent screening
• Participation in another study that could interfere with the risk of ICU-acquired colonization and infection with MDR bacteria