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| Name | Class |
|---|---|
| University of Oslo | OTHER |
| Oslo University Hospital | OTHER |
| Helse Nord-Trøndelag HF | OTHER |
| University of Groningen |
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In this study, all citizen of Nord-Trøndelag County, Norway, above 20 years of age are invited to participate in a population-based health study, the HUNT study. Blood samples are drawn from the participants and assessed for celiac disease by a serological assay. Celiac disease is a chronic inflammatory disease of the small intestine due to dietary gluten in wheat, barley and rye. The diagnosis will be verified through endoscopic assessment and biopsies from the small intestinal mucosa. The aims of the study are 1) to establish the population-based prevalence of celiac disease; 2) to assess the consequences of the disease from patient reported outcomes, symptoms, deficiencies, and co-morbidity; 3) to study possible risk factors and environmental triggering events; 4) to identify genetic predictors and gene-environmental interactions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Endoscopy and biopsy | Other | Participants of the HUNT study with a positive serological assay for celiac disease are invited to attain a diagnostic endoscopy with duodenal biopsies |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endoscopy and biopsy | Diagnostic Test | Participants with a positive celiac serology are assessed by endoscopy and duodenal biopsy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of celiac disease | the proportion of cases in the general population of Nord-Trøndelag County, Norway | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Eivind Ness-Jensen, md phd | NTNU, Norwegian University of Science and Technology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Levanger Hospital, Nord-Trøndelag Hospital Trust | Levanger | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38195172 | Derived | Lukina P, Andersen IL, Eggen PT, Mjones PG, Ronne E, Bolstad N, Klaasen RA, Warren DJ, Iversen R, Hveem K, Bernklev T, Jelsness-Jorgensen LP, Pedersen L, Jonkers I, Lagergren P, Sollid LM, Lundin K, Ness-Jensen E. Coeliac disease in the Trondelag Health Study (HUNT), Norway, a population-based cohort of coeliac disease patients. BMJ Open. 2024 Jan 9;14(1):e077131. doi: 10.1136/bmjopen-2023-077131. |
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| ID | Term |
|---|---|
| D002446 | Celiac Disease |
| D004194 | Disease |
| ID | Term |
|---|---|
| D008286 | Malabsorption Syndromes |
| D007410 | Intestinal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| ID | Term |
|---|---|
| D004724 | Endoscopy |
| D001706 | Biopsy |
| ID | Term |
|---|---|
| D003949 | Diagnostic Techniques, Surgical |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D019060 | Minimally Invasive Surgical Procedures |
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| OTHER |
| Karolinska Institutet | OTHER |
All inhabitants of Nord-Trøndelag County, Norway, above 18 years of age are invited to participate
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| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D013514 | Surgical Procedures, Operative |
| D003581 | Cytodiagnosis |
| D003584 | Cytological Techniques |
| D019411 | Clinical Laboratory Techniques |
| D013048 | Specimen Handling |
| D008919 | Investigative Techniques |