Evaluation of Vaginal Self-sampling Diagnostic Performances to Identify Genital Infections

Evaluation of Vaginal Self-sampling Diagnostic Performances to Identify Genital Infections : A Large, Cross-sectional, Non-inferiority Trial

Screening for genital infection (GI), sexually transmitted infection (STI) and asymptomatic carriage of group B streptococcus (GBS) in pregnant women is a common reason for medical appointments. Conventional testing is performed by using vaginal and/or cervical classic sampling (VCS). Vaginal self-sampling (VSS) has progressively emerged as an alternative to VCS for STI agent screening. The use of vaginal self-sampling (VSS) could facilitate follow-ups and potentially help in the prevention of gynaecological disorders.

Inclusion Criteria:

• Women requiring vaginal or cervical classical sampling to screen for genital infections
• Women requiring vaginal or cervical classical sampling to screen for sexually transmitted infections (STI)
• Pregnant women requiring vaginal classical sampling to screeen for Group B streptococcus asymptomatic carriage in the eighth month of pregnancy
• Informed written consent from the patient

Exclusion Criteria:

• Person subjected to therapeutic limitation decision
• Women with intact hymen
• Active antibiotic or antifungic treatment
• Antiobiotic or antifungic treatment during the 10 days prior to inclusion