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| Name | Class |
|---|---|
| Vital Strategies | OTHER |
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The objectives of this study are to:
The investigators also aim to:
1. To determine the total time required to obtain a BP measurement.
Hypertension guidelines recommend a minimum of five minute rest time prior to blood pressure (BP) measurements obtained for screening, diagnosis and management of hypertension. This recommended wait time is often not adhered to and is cited as a barrier to regular screening due to length of time, clinic workflow and provider burden. It is unclear if BPs obtained at different rest intervals would provide clinically similar measurements. This study therefore aims to determine if BPs obtained immediately or after 2 minutes are rest are non-inferior to the BPs obtained after the guideline recommended 5 minutes of rest. It also aims to determine the time required to measure BP from start to finish, to allow for easier identification of other potential barriers to regular BP screening practices in busy clinical settings.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 0-2-5-5 minutes rest group | Other | The order of rest periods for participants randomized to this arm will be: 0 minutes 2 minutes 5 minutes 5 minutes |
|
| 0-5-2-5 minutes rest group | Other | The order of rest periods for participants randomized to this arm will be: 0 minutes 5 minutes 2 minutes 5 minutes |
|
| 2-0-5-5 minutes rest group | Other | The order of rest periods for participants randomized to this arm will be: 2 minutes 0 minutes 5 minutes 5 minutes |
|
| 5-0-2-5 minutes rest group | Other | The order of rest periods for participants randomized to this arm will be: 5 minutes 0 minutes 2 minutes 5 minutes |
|
| 2-5-0-5 minutes rest group | Other | The order of rest periods for participants randomized to this arm will be: 2 minutes 5 minutes 0 minutes 5 minutes |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Timing of rest prior to blood pressure measurement | Other | Each participant will have 4 sets of 3 blood pressure measurements taken. The participants will be randomized to the order in which they rest prior to each set of measurements. |
| Measure | Description | Time Frame |
|---|---|---|
| Difference in Systolic Blood Pressure (mmHg) | Comparison of the average of 3 systolic BP measurements (mmHg) measured after 5 minutes rest with the average of 3 systolic blood pressure (SBP) measured after the other periods of rest (0 minutes, 2 minutes, second 5 minutes of rest) | 90 minutes |
| Difference in Diastolic Blood Pressure (mmHg) | Comparison of the average of 3 diastolic BP measurements (mmHg) measured after 5 minutes rest with the average of 3 diastolic blood pressure (DBP) measured after the other periods of rest (0 minutes, 2 minutes, second 5 minutes of rest) | 90 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Blood Pressure Variability (mmHg) | Difference between individual systolic and diastolic BP measurements (BP reading 1 - BP reading 2; BP reading 2 - BP reading 3) obtained per each rest period | 90 minutes |
| Standard Deviation of Blood Pressures (mmHg) |
| Measure | Description | Time Frame |
|---|---|---|
| Total time required to obtain a BP measurement (seconds) | For each rest time assignment, mean time from:
| 90 minutes |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Tammy Brady, MD, PhD | Johns Hopkins University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Johns Hopkins School of Medicine Division of Pediatric Nephrology | Baltimore | Maryland | 21287 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34601959 | Result | Brady TM, Charleston J, Ishigami J, Miller ER 3rd, Matsushita K, Appel LJ. Effects of Different Rest Period Durations Prior to Blood Pressure Measurement: The Best Rest Trial. Hypertension. 2021 Nov;78(5):1511-1519. doi: 10.1161/HYPERTENSIONAHA.121.17496. Epub 2021 Oct 4. |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| D002318 | Cardiovascular Diseases |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
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| 5-2-0-5 minutes rest group | Other | The order of rest periods for participants randomized to this arm will be: 5 minutes 2 minutes 0 minutes 5 minutes |
|
Difference in standard deviation of the mean of 3 systolic and diastolic BPs obtained at each rest period
| 90 minutes |
| Coefficient of Variation of Blood Pressures | Difference in coefficient of variation (SD/mean) of 3 systolic and diastolic BPs obtained at each rest period | 90 minutes |