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The goal of this is to evaluate the biomechanical properties of hypotonous eyes with vertical anterior corneal striae and/or hypotony maculopathy compared to hypotonous eyes without striae.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Anterior Cornea Striae | Eyes with anterior cornea striae present |
| |
| Hypotony Maculopathy | Eyes with hypotony maculopathy present |
| |
| Hypotony only | Eyes with intraocular pressure less than 10 without cornea striae and/or maculopathy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ophthalmic imaging | Other | Optical coherence tomography Topography Ocular Response Analyzer Optical Biometry Slit lamp photos |
|
| Measure | Description | Time Frame |
|---|---|---|
| Corneal hysteresis | Difference in postoperative corneal hysteresis (measured in mm Hg) by Ocular Response Analyzer, between study arms | Baseline |
| Incidence of anterior corneal striae | Frequency of occurrence among all enrolled hypotonous eyes | Baseline |
| Incidence of hypotony maculopathy | Frequency of occurrence among all enrolled hypotonous eyes | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Axial length | Difference in postoperative axial length between study arms | Baseline |
| Corneal thickness | Difference in postoperative corneal thickness between study arms |
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Inclusion Criteria:
Exclusion Criteria:
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Subjects >= 18 years of age with a history of glaucoma and glaucoma surgery
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| Name | Affiliation | Role |
|---|---|---|
| Leon Herndon, MD | Duke University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Duke University Health System | Durham | North Carolina | 27705 | United States |
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| ID | Term |
|---|---|
| D015814 | Ocular Hypotension |
| D008268 | Macular Degeneration |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
| D012162 | Retinal Degeneration |
| D012164 | Retinal Diseases |
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| Baseline |
| Corneal curvature | Difference in postoperative diopters of steepest cornea axis, flattest cornea axis and astigmatism between study arms | Baseline |
| Corneal resistance factor | Difference in postoperative corneal resistance factor between study arms | Baseline |