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The main goal of this clinical trial is to use a novel exercise intervention to improve cardiometabolic and biopsychosocial health outcomes in overweight/obese sedentary survivors of AYA cancers at risk for chronic comorbid conditions. The investigator's hypothesis is that an exercise intervention will improve: cardiometabolic health; body composition; physical fitness and biopsychosocial outcomes when compared to the attention control group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exercise | Active Comparator | Will receive the exercise intervention |
|
| Attention Control | No Intervention | Will not receive the exercise intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise | Other | personalized exercise prescription |
|
| Measure | Description | Time Frame |
|---|---|---|
| Cardiometabolic health - Insulin Resistance | insulin resistance estimated by HOMA from a fasting blood sample | change from baseline to 4 months, to 8 months to 1 year |
| Cardiometabolic health - metabolic syndrome waist circumference | markers of metabolic syndrome, waist circumference via measuring tape (cm) | change from baseline to 4 months, to 8 months to 1 year |
| Cardiometabolic health - metabolic syndrome blood pressure | markers of metabolic syndrome, blood pressure via Omron cuff (mmHg) | change from baseline to 4 months, to 8 months to 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Body Composition | fat mass and lean mass via DEXA (reported in lbs) | change from baseline to 4 months, to 8 months to 1 year |
| Cardiorespiratory fitness (Physical Fitness) | cardiorespiratory fitness via submaximal VO2 max (reported via ml/kg/min) |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| change from baseline to 4 months, to 8 months to 1 year |
| Muscular Strength (Physical Fitness) | muscle strength through multiple repetition maximum (lbs) | change from baseline to 4 months, to 8 months to 1 year |