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| Name | Class |
|---|---|
| Jupiter Hospital, India | UNKNOWN |
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The Investigator would like to study the effect of yoga exercises and meditation on lung volume, respiratory impedance, 6-minute walk distance and quality of life in COPD patients.
Hypotheses : The Investigator hypothesized that Yoga exercises improve the lung function (i.e. decrease in the lung hyperinflation, air trapping and airway impedance) by stretching the lung tissue, strengthening the respiratory muscles and increasing the chest expansion. Yoga exercises help to increase exercise capacity. Meditation reduces anxiety and depression.
Research Question: Do yoga exercises and meditation help to reduce respiratory impedance, hyperinflation, air trapping and increase exercise capacity and improve quality of life in COPD patients compared to control arm?
Objectives: 1. To study the effect of yoga exercises and meditation on exercise capacity and quality of life in COPD patients after 4, 8 and 12-weeks of intervention.
2.To evaluate residual volume (RV), residual volume/ total lung volume RV/TLC, total lung capacity TLC,inspiratory capacity/total lung capacity IC/TLC, and respiratory impedance in COPD patients after 4, 8 and 12-weeks of yoga exercises and meditation practice.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Effect of yoga exercises in COPD patients after 12 weeks. | Experimental | Yoga group |
|
| COPD patients lung functions without yoga excercises. | No Intervention | Control group |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Yoga breathing exercises and Meditation | Other | 8 Breathing exercises.The first set of 6 exercises is of the Upper Lobe breathing (Upper and Middle Lobe of the Lungs) while 7th exercise is abdominal breathing,8th exercise is yogic breathing. 6-steps Nirmal Dhyan (meditation).Step 1: Breath awareness,Step 2: Body awareness,Step 3: Thought awareness,Step 4: Refreshing awareness,Step 5: Gap awareness,Step 6: Expanding awareness. |
| Measure | Description | Time Frame |
|---|---|---|
| St.George's Respiratory Questionnaires (SGRQ) score for quality of life in numbers. | Effect of Yoga Exercises and Meditation on SGRQ score after 12 week in COPD patients. | 3 Months |
| Exercise capacity 6 minute walk distance (6MWD) in meter. | Effect of Yoga Exercises and Meditation on 6 minute walk distance (6 MWD) after 12 week in COPD patients. | 3 Months. |
| Measure | Description | Time Frame |
|---|---|---|
| RV/TLC in% | Effect of Yoga Exercises and Meditation on lung function after 12 week in COPD patients. | 3 Months |
| TLC in liters | Effect of Yoga Exercises and Meditation on lung function after 12 week in COPD patients. |
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Inclusion Criteria:
Exclusion Criteria:
Active smoker.
Pregnant women or nursing mothers. (Urine pregnancy test will be performed.)
Those unable to perform spirometry and body plethysmography.
Participants having symptoms of active pulmonary Koch's (tuberculosis).
Contraindications for spirometry: Subject having any of the following contraindications for spirometry.
History of the following a) Recent (within 1 month) myocardial infarction. b) Unstable heart condition c) Hemoptysis (blood in sputum on coughing) in recent past (1 month) or d) A recent (within last one month) eye, chest or abdominal surgery.
Contraindications for Body Plethysmography: Subject having any of the following contraindications for body plethysmography
Anyone who is on continuous oxygen therapy
Patients who are doing yoga or taking pulmonary rehabilitation from last 6 months.
History of thoracic cage abnormality, musculoskeletal abnormality, interstitial lung disease, epilepsy
Patients who are unable to perform yoga exercises.
Contraindications for 6 Minute walk test:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Nitin Vanjare, M.Sc. | Contact | +91 9970537116 | vanjarenitin@crfindia.com | |
| Shweta Rasam, B.Sc. | Contact | +91 9881133834 | shweta@crfindia.com |
| Name | Affiliation | Role |
|---|---|---|
| Dr. Sundeep Salvi, MD | Director | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chest Research Foundation | Recruiting | Pune | Maharashtra | 411014 | India |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19249998 | Background | Donesky-Cuenco D, Nguyen HQ, Paul S, Carrieri-Kohlman V. Yoga therapy decreases dyspnea-related distress and improves functional performance in people with chronic obstructive pulmonary disease: a pilot study. J Altern Complement Med. 2009 Mar;15(3):225-34. doi: 10.1089/acm.2008.0389. | |
| 28714735 | Background |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D008173 | Lung Diseases, Obstructive |
| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
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| ID | Term |
|---|---|
| D019122 | Meditation |
| ID | Term |
|---|---|
| D026441 | Mind-Body Therapies |
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D026443 | Spiritual Therapies |
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|
| 3 Months |
| Respiratory impedance in kpa/(L/s) | Effect of Yoga Exercises and Meditation on lung function after 12 week in COPD patients. | 3 Months |
| Kaminsky DA, Guntupalli KK, Lippmann J, Burns SM, Brock MA, Skelly J, DeSarno M, Pecott-Grimm H, Mohsin A, LaRock-McMahon C, Warren P, Whitney MC, Hanania NA. Effect of Yoga Breathing (Pranayama) on Exercise Tolerance in Patients with Chronic Obstructive Pulmonary Disease: A Randomized, Controlled Trial. J Altern Complement Med. 2017 Sep;23(9):696-704. doi: 10.1089/acm.2017.0102. Epub 2017 Jul 17. |
| 24977005 | Result | Liu XC, Pan L, Hu Q, Dong WP, Yan JH, Dong L. Effects of yoga training in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis. J Thorac Dis. 2014 Jun;6(6):795-802. doi: 10.3978/j.issn.2072-1439.2014.06.05. |
| D010335 |
| Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012064 |
| Relaxation Therapy |
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |