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We aimed to use Raman spectroscopy to detect differences between healthy controls and patients with surgically proven endometriosis.
Endometriosis is a chronic disease whose molecular basis is still unknown and diagnostic methods are controversial. The diagnosis is still invasive and there are no accepted ways which are molecular-based and noninvasive. Raman spectroscopy is a vibrational spectroscopy technique which can analyze specific spectral patterns, substances and molecular changes with high specificity. We aimed to use Raman spectroscopy to detect differences between healthy controls and patients with surgically proven endometriosis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control | Experimental | healthy controls |
|
| patient | Experimental | patients diagnosed with endometriosis |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| raman analysis | Diagnostic Test | negative or pozitive |
|
| Measure | Description | Time Frame |
|---|---|---|
| diagnostic specificity | differentiating endometriosis patients from healthy controls by computer based technology designed with raman data | 2 years |
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Inclusion Criteria:
Exclusion Criteria:
females have endometriosis
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bahar Yuksel | Contact | 05424732003 | baharyl86@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Bahar Yuksel, md | esenler maternity and children's hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bahar Yuksel | Recruiting | Istanbul | 34000 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26277185 | Background | Lyng FM, Traynor D, Ramos IR, Bonnier F, Byrne HJ. Raman spectroscopy for screening and diagnosis of cervical cancer. Anal Bioanal Chem. 2015 Nov;407(27):8279-89. doi: 10.1007/s00216-015-8946-1. Epub 2015 Aug 16. | |
| 25872466 | Background | Eberhardt K, Stiebing C, Matthaus C, Schmitt M, Popp J. Advantages and limitations of Raman spectroscopy for molecular diagnostics: an update. Expert Rev Mol Diagn. 2015 Jun;15(6):773-87. doi: 10.1586/14737159.2015.1036744. Epub 2015 Apr 15. |
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only by request
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| ID | Term |
|---|---|
| D004715 | Endometriosis |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| D000091662 | Genital Diseases |