Infant Formula With Partially Hydrolyzed Cow's Milk Protein Versus a Formula With Intact Protein

Randomized, Parallel, Double-blind Study With a Partially Hydrolyzed Infant Formula With Cow's Milk Protein vs a Formula With Intact Protein to Assess Growth and Impact on the Gastrointestinal Manifestations of Colic in the Healthy Infant.

Randomized, parallel, double-blind clinical trial, comparing a partially hydrolyzed serum proteins infant formula with a conventional formula with intact protein in healthy infants that suffer from colic

Demonstrate that an infant formula with partially hydrolized cow's milk protein of serum proteins is equivalent to an intact protein formula in healthy children in terms of safety of use and suitability, to prove that it can be a alternative with digestive health benefits in healthy children with infant colic.

Inclusion Criteria:

• Children diagnosed as nursing colic according to Roma IV criteria.
• Infants who have received breastfeeding at least 2 weeks.
• Infants who at the time of inclusion in the study whose parents/legal guardians voluntarily decide not to continue exclusive breastfeeding or only maintain it in residual form (less than 20% of the daily intake, one breast intake per day).
• Full-term infants (>37 weeks of gestation).
• Infants with weight suitable for their gestational age (2500-4500g).
• Normal APGAR score: 7-10.
• Infants between 2 and 8 weeks of life.
• Infants whose parents/legal guardians have signed informed consent.
• Infants with good availability of clinical follow-up until the end of the study.

Exclusion Criteria:

• Infants fed from birth with exclusive infant formula.
• Infants with congenital diseases or malformations that may affect growth.
• Infants with major medical conditions that require chronic medication or close medical checks.
• Infants who have taken any type of antibiotics or probiotics prior to the study.