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This study objectively held to compare the physiological outcomes in the non-invasive (NIV) treatment of Acute Cardiogenic Pulmonary Edema (ACPE) patients in the Emergency Department (ED) delivered by helmet CPAP (hCPAP) and facemask CPAP (fCPAP).Patients will be randomized to receive either hCPAP or fCPAP.
Non-invasive ventilation(NIV) has different types of interfaces that had been used in acute cardiogenic pulmonary edema. The appropriate interface is necessary to provide comfort and lead to the success of NIV.
NIV delivered via facemask had been used widely. However, it was associated with leaks and discomfort to the patient.
Helmet continuous positive airway pressure (hCPAP) is an NIV interface that allows the provision of high airway pressures with a minimal leak.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| helmet CPAP | Active Comparator | helmet CPAP administer to patient diagnosed as acute cardiogenic pulmonary edema |
|
| facemask CPAP | Active Comparator | facemask CPAP administer to patient diagnosed as acute cardiogenic pulmonary edema |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| hCPAP vs fCPAP | Device | The patient presented with Acute Cardiogenic Pulmonary Edema will be randomized into either helmet CPAP or facemask CPAP. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Respiratory Rate | Respiratory rate change post intervention | 1 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Heart Rate | Heart rate change post intervention | 1 hour |
| Partial Pressure of Arterial Oxygen Level | Partial arterial oxygen level post intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Adi Osman | Emergency Department, Hospital Raja Permaisuri Bainun | Principal Investigator |
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| ID | Term |
|---|---|
| D011654 | Pulmonary Edema |
| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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| 1 hour |
| Ratio Of Partial Pressure Arterial Oxygen And Fraction Of Oxygen | Partial arterial oxygen/fraction of oxygen ratio change post intervention | 1 hour |
| Dyspnea Scale | Dyspnea scale improvement post intervention.Dyspnea scale measured using an unmarked 100mm VAS card that had mark with "I can breathe normally", at one end correspond to patients' normal baseline breathing which score "0" and on the other end "I can't breathe at all", which score "100" represent the worst difficulty perceived by patients. | 1 hour |
| Partial Pressure of Arterial Carbon Dioxide level | Partial Pressure of Arterial Carbon Dioxide level change post intervention. | 1 hour |
| Rate of Intubation | Intubation rate post intervention | 1 hour |