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| Name | Class |
|---|---|
| Tamer Mohamed Naguib | UNKNOWN |
| Amr Ahmed Magdy | UNKNOWN |
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After preoperative preparation patient is shifted to operating theater, with all monitors applied. She will receive spinal block at lumbar 3-4 space with hyperbaric bupivacaine 8 mg plus 25 mic fentanyl. After giving anesthesia and positioning for surgery with a left lateral tilt of 15 degrees,
Pregnant women which are listed to undergo elective caeserian section for single viable baby under spinal anesthesia.
Exclusion criteria:
On arrival of patients to pre-anaesthesia preparation room, we will allow patients to rest in supine position with 15 degree left tilt by pillow wedge under right hip, after allowing patient to rest for five minutes, measures are recorded: ECG , heart rate, non invasive blood pressure, pulse oximeter applied on the index finger of the limb not attached to the blood pressure cuff, pulse oximetry and Plethysmography variability index (PVI) and perfusion index (PI) will be taken by (Massimo radical 7, Massimo corp. USA). Measures will be recorded every 5 minutes preoperative. Patients with PVI <15 are excluded from the study.
Patients with PVI > 15 are started on intravenous infusion of warm ringer lactate solution via suitable pore intravenous cannula to reach target of PVI <15 or a total 1 liter of ringer lactate.
The patients in which the PVI is corrected by fluid to level below 15 will be Group (C) or corrected group. Patients in which intravenous fluid administration did not result any change in PVI or changed but still higher than 15 will be Group (NC) or non corrected group.
After preoperative preparation patient is shifted to operating theater, with all monitors applied. She will receive spinal block at lumbar 3-4 space with hyperbaric bupivacaine 8 mg plus 25 mic fentanyl. After giving anesthesia and positioning for surgery with a left lateral tilt of 15 degrees, supplemental oxygen at rate of 4 liter/minute is applied.
Measurements will be taken every minute till delivery of the baby, and if the blood pressure is decreased below 20% of the baseline level before anesthesia, patients will be given incremental doses of ephedrine sulfate 0.1 mg /kg till blood pressure normalized above 80% of pre-anesthesia level. All measurements will be recorded in tables and subjected to statistical analysis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Corrected group | The patients in which the PVI will corrected by fluid to level below 15 |
| |
| Uncorrected group | Patients in which intravenous fluid administration didn't result any change in PVI or changed but still higher than 15 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Spinal Anesthesia | Procedure | The patients will receive spinal block at lumbar 3-4 space with hyperbaric bupivacaine 8 mg plus 25 mic fentanyl. After giving anesthesia and positioning for surgery with a left lateral tilt of 15 degrees, supplemental oxygen at rate of 4 liter/minute is applied. |
| Measure | Description | Time Frame |
|---|---|---|
| The incidence of post-spinal anesthesia hypotension | The decrease in the mean arterial pressure below 65 mmHg or below 80% of the baseline value. | Through out the whole intraoperative period |
| Measure | Description | Time Frame |
|---|---|---|
| The consumption of vasopressors | The total dose of ephedrine required to maintain the MAP above 80% of the baseline value | Through out the whole intraoperative period |
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Inclusion Criteria:
Exclusion Criteria:
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Full term pregnant female patients presented for elective cesarean section delivery of a single viable fetus under spinal anesthesia/
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| Name | Affiliation | Role |
|---|---|---|
| Sameh Ismaiel, M.D | Lecturer of Anesthesia and Intensive Care, Tanta University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tanta University Hospitals | Tanta | Algharbia Governate | 31511 | Egypt | ||
| Tanta University hospitals |
Once the study had been successfully completed, the data will be shared for other researchers.
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| ID | Term |
|---|---|
| D000775 | Anesthesia, Spinal |
| ID | Term |
|---|---|
| D000765 | Anesthesia, Conduction |
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
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|
| Tanta |
| 31511 |
| Egypt |