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| Name | Class |
|---|---|
| American Academy of Neurology | OTHER |
| Tourette Association of America | OTHER |
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This is a single-arm open trial of Comprehensive Behavioral Intervention for Tics (CBIT) delivered to pediatric and adult patients with persistent tic disorders in their homes via videoconferencing (i.e., teleCBIT). All participants who enroll will receive teleCBIT.
Comprehensive Behavioral Intervention for Tics (CBIT) is a behavioral therapy with proven efficacy for treating persistent tic disorders (e.g., Tourette Syndrome) in youth and adults. Lack of access to a local CBIT provider prevents treatment access for many patients who could benefit from CBIT. Providing CBIT to patients in their homes via videoconferencing technology (i.e., teleCBIT) is a promising approach to increasing CBIT access. This study investigates treatment uptake, acceptability, feasibility, and clinical effectiveness of teleCBIT among pediatric and adult patients enrolled as patients in a state-of-the-art medical tic program.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| teleCBIT | Experimental | Patient receive eight sessions of individual teleCBIT, in accordance with Woods et al's (2008) protocol, from a licensed psychologist. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| teleCBIT | Behavioral | Eight sessions of individual behavior therapy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Yale Global Tic Severity Scale Tic Severity Score (YGTSS) | YGTSS Tic Severity Score (0-50) as rated by independent evaluator. Higher scores indicate more severe tics. | Change from pre-treatment (i.e., week 0) to post-treatment (i.e., 10-week) |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical Global Impression: Improvement (CGI:I) Score | CGI:I scores (range: 1-7) describe the global level of change in clinical severity of a disorder. Lower scores indicate more favorable change over time. Following common practice, we will also dichotomize CGI:I scores to evaluate Clinical Responder Status according to CGI:I score (i.e., responder: CGI:I=1 or 2; non-responder=CGI:I>2) | CGI:I score at post-treatment (Week 10), which assesses change from pre-treatment (i.e., week 0) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| San Jose State University | San Jose | California | 95192 | United States | ||
| University of Florida Health |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37545359 | Derived | Capriotti MR, Wellen BC, Young BN, Himle MB, Conelea CA, Espil FM, Simpson H, Mathews CA. Evaluating the feasibility, acceptability, and preliminary effectiveness of tele-comprehensive behavior therapy for tics (teleCBIT) for Tourette syndrome in youth and adults. J Telemed Telecare. 2025 Apr;31(3):328-337. doi: 10.1177/1357633X231189305. Epub 2023 Aug 7. |
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| ID | Term |
|---|---|
| D013981 | Tic Disorders |
| D005879 | Tourette Syndrome |
| ID | Term |
|---|---|
| D009069 | Movement Disorders |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D065886 | Neurodevelopmental Disorders |
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True masking not possible due to single-arm design. However, independent evaluator is blind to treatment utilization and progress.
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| Parent Tic Questionnaire (PTQ) Total Tic Severity Score | Child Tic Severity as measured by parent-report on the PTQ (range: 0-224). Higher scores indicate more severe tics. | Change from pre-treatment (i.e., week 0) to post-treatment (i.e., 10-week) |
| Adult Tic Questionnaire (ATQ) Total Tic Severity Score | Adult Tic Severity as measured by self-report on the ATQ (range: 0-224). Higher scores indicate more severe tics. | Change from pre-treatment (i.e., week 0) to post-treatment (i.e., 10-week) |
| Yale Global Tic Severity Scale (YGTSS) Impairment Score | YGTSS Impairment Score (0-50) as rated by independent evaluator. Higher scores indicate greater tic-related impairment | Change from pre-treatment (i.e., week 0) to post-treatment (i.e., 10-week) |
| Gainesville |
| Florida |
| 32606 |
| United States |
| D001523 | Mental Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D020271 | Heredodegenerative Disorders, Nervous System |
| D019636 | Neurodegenerative Diseases |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |