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The aim of this 18 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) dentifrices when used up to 3 months on dental plaque relative to a positive or negative control dentifrice.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Stannous Fluoride Dentifrice | Twice daily brushing |
| |
| Positive control dentifrice | Twice daily brushing |
| |
| Negative control dentifrice | Twice daily brushing |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Stannous fluoride dentifrice | Drug | Stannous fluoride (0.454%) dentifrice |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Dental Plaque Scores | Change from baseline as measured by mean plaque score reduction from baseline (via Quigley-Hein, Turesky Modification Index or Rustogi Modification of the Navy Plaque index). | Up to 12 weeks |
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Subjects were excluded from this study for the following reasons;
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This meta-analysis includes healthy adult male and females.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Multiple P&G Investigation Clinical Sites | Cincinnati | Ohio | 45040 | United States |
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| ID | Term |
|---|---|
| D003773 | Dental Plaque |
| ID | Term |
|---|---|
| D003741 | Dental Deposits |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| Positive control dentifrice |
| Drug |
Positive control dentifrice containing (0.3%) triclosan. |
|
| Negative control dentifrice | Drug | Negative control dentifrice containing either sodium fluoride (0.243%) or sodium monofluorophosphate (0.76%) |
|