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| Name | Class |
|---|---|
| Beijing Institute of Otolaryngology | UNKNOWN |
| Shanghai Johnson & Johnson Pharmaceuticals, Ltd. | UNKNOWN |
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Chronic rhinitis (CR) is one of the most common nasal mucosal diseases in the world. In China, about 140 million people suffer from this disease. Chronic rhinitis can lead to severe economic and social burden, as well as the potential risk of developing other chronic diseases such as asthma and chronic sinusitis. Therefore, it is of great significance to explore the classification and treatment strategies of chronic rhinitis in order to improve the health level of Chinese people.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A: Placebo group | Placebo Comparator | Treated by 0.9% Natural saline (NS) nasal spray: 2 sprays each side daily in the morning |
|
| B: Budesonide Nasal Spray (Rhinocort) | Experimental | Treated by Budesonide Nasal Spray (Rhinocort, Shanghai Johnson & Johnson Pharmaceuticals, Ltd.) nasal spray: 2 sprays each side daily in the morning |
|
| C: Levocabastine Nasal Spray (Livostine) | Experimental | Treated by Levocabastine(Livostinet, Shanghai Johnson & Johnson Pharmaceuticals, Ltd.) Nasal Spray: 2 sprays each side daily in the morning |
|
| D: Combined Treatment | Experimental | Treated by Budesonide Nasal Spray (Rhinocort, Shanghai Johnson & Johnson Pharmaceuticals, Ltd.) nasal spray: 2 sprays each side daily in the morning and Levocabastine(Livostinet, Shanghai Johnson & Johnson Pharmaceuticals, Ltd.) Nasal Spray: 2 sprays each side daily in the morning |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Budesonide Nasal Spray (Rhinocort, Shanghai Johnson & Johnson Pharmaceuticals, Ltd.) | Drug | Detailed in arm descriptions |
|
| Measure | Description | Time Frame |
|---|---|---|
| Relief of bothersome symptoms | Determined by change of visual analog scale for symptoms | 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beijing Tongren Hospital | Recruiting | Beijing | Beijing Municipality | 100730 | China |
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| Levocabastine Nasal Spray (Livostine, Shanghai Johnson & Johnson Pharmaceuticals, Ltd.) | Drug | Detailed in arm descriptions |
|
| 0.9% natural saline | Drug | Detailed in arm descriptions |
|
| Yifan Meng | Recruiting | Beijing | Beijing Municipality | 100730 | China |
|
| ID | Term |
|---|---|
| D019819 | Budesonide |
| D036881 | Long-Term Synaptic Depression |
| ID | Term |
|---|---|
| D011282 | Pregnenediones |
| D011283 | Pregnenes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
| D009473 | Neuronal Plasticity |
| D009424 | Nervous System Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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