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Despite aortic coarctation (CoA) repair these patients have cardiovascular complications and coronary artery disease is the most common cause of death.
The aim with this study was to measure intima-media thickness (IMT) and plaques in arteries compared to cardiovascular markers in controls and patients with CoA.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Subjects with coarctation |
| ||
| Controls |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ultrasound measurement | Other | Ultrasound measurement |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intima-media thickness | Measurement in mm | Intima-media thickness will be measured at one time point namely at inclusion. Data will be reported when study is completed, an average of 2 year. |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiovascular markers | A multiplex platform to analyze circulating blood levels biomarkers was used. | Blood samples will be taken at one time point namely at inclusion. Then biomarkers will be analysed when study is completed. Data will be reported when study is completed, an average of 2 year. |
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Inclusion Criteria:
Exclusion Criteria:
sex and age-matched controls
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Patients with aortic coarctation
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34564048 | Derived | Hlebowicz J, Holm J, Lindstedt S, Goncalves I, Nilsson J. Carotid atherosclerosis, changes in tissue remodeling and repair in patients with aortic coarctation. Atherosclerosis. 2021 Oct;335:47-52. doi: 10.1016/j.atherosclerosis.2021.09.016. Epub 2021 Sep 21. |
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| ID | Term |
|---|---|
| D050197 | Atherosclerosis |
| D001017 | Aortic Coarctation |
| ID | Term |
|---|---|
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| D006330 |
| Heart Defects, Congenital |
| D018376 | Cardiovascular Abnormalities |
| D006331 | Heart Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |