Immunogenicity of Cholera Vaccine in Children With IBD

Evaluation of Immunogenicity of Cholera Vaccine in Children With Inflammatory Bowel Disease

Assessment of the immunogenicity and safety of immunization against cholera in children with inflammatory bowel disease.

Inclusion Criteria:

• diagnosis of Crohn's disease or ulcerative colitis based on standard clinical, endoscopic, histologic and radiographic criteria (Porto criteria),
• no vaccination against cholera in the past,
• written consent of the patient's legal guardians and the patient himself if he/she turns 16 years of age.

Exclusion Criteria:

• serious exacerbation of inflammatory bowel disease defined as Paediatric Ulcerative Colitis Activity Index (PUCAI) > 65 points for patients with ulcerative colitis or Pediatric Crohn's Disease Activity Index (PCDAI) > 40 points for patients with Crohn's disease.