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| ID | Type | Description | Link |
|---|---|---|---|
| 364485 | Other Grant/Funding Number | CIHR |
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| Name | Class |
|---|---|
| Université du Québec a Montréal | OTHER |
| University of Toronto | OTHER |
| Laval University | OTHER |
| Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal |
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About 18% of independent people over 65 who are evaluated in Emergency Departments for minor injuries (fractures, sprains) present some mobility decline up to 3 to 6 months postinjury. People at risk of decline are prefrail or frail; this condition could be explained by muscle proprieties loss. Exercise is a proven method that can help limit frailty and allow to restore mobility.
The aim of our study is to evaluate whether a suitable exercise program of one hour, twice a week for 12 weeks will limit functional losses & fragility in injured older adults after their emergency department visit.
Yearly, around 400 000 Canadian community-dwelling seniors sustain injuries that are not life threatening but limit their mobility and normal activities. Up to 65 % of these seniors seek care in Emergency Departments (EDs) and 2/3 are discharged from EDs with varying degrees of minor injuries. Since 2010 and using multicenter large Canadian cohorts (n=3000), our CIHR CETI* emerging team has shown that minor injuries trigger a downward spiral of mobility decline in 16% of seniors who are still independent at the time of injury, unmasking early impairments and a prefrail or frail status. As there are no ED management guidelines designed to prevent these prefrail (35%) and frail (13%) injured seniors from losing their mobility and function, they do deteriorate within 6 months post-ED discharge. This is unfortunate because there is compelling evidence of the effectiveness of community and home-based mobility interventions showing that simple, targeted interventions can prevent frailty and functional limitations.
In that context, identification of seniors at risk in EDs is crucial to implement effective interventions. The CETI has validated a simple Clinical Decision Rule (CETI-CDR) that screens and orients seniors at high, moderate and low risk of functional decline to appropriate post-ED follow-ups. The latter include effective community-based mobility interventions available across all Canadian communities. An ongoing pilot study (n=120) in two EDs is showing the feasibility and effectiveness (functional decline prevention) of interventions and patient satisfaction. The investigators thus propose to implement the CEDeComS intervention, which involves the CETI-CDR combined with rapid linkage to community mobility programs directly from EDs.
The Main Objectives of this study are to 1) evaluate the effectiveness of the CEDeComS compared to usual care, on improving seniors' health outcomes, 2) determine the cost-effectiveness of the intervention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| intervention | Experimental | EDs 1 to 7 will then be randomly phased-in INT every 3 months. |
|
| control | No Intervention | During the first 6 months and throughout CTRL time |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise program | Other | Exercise program in communities / Exercise program at home |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Cumulative Incidence of Functional Decline at 3 and 6 months after the intial ED visit (Baseline) | Proportions of participants showing, at 3 or 6 months post-ED visit, a loss ≥2/28 on the OARS scale, compared to Baseline. (OARS: Older American Resource and Services multidimensional functional scale, which includes 7 basic ADLs and 7 instrumental ADLs items) | Outcome measures are assessed at three time points : Baseline T0: time of the Emergency Department (ED) consultation by participants T1: 3 months post-ED consultation; T2: 6 months post-ED consultation |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in mean SPPB scores at 3 and 6 months after the initial ED visit (baseline) | The SPPB (Short Physical Portable Battery) combines walking, balance and strength items. Scores range from 0 to 12 (best). | Outcome measures are assessed at three time points : Baseline T0: time of the Emergency Department (ED) consultation by participants T1: 3 months post-ED consultation; T2: 6 months post-ED consultation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Marie-Josée MJ Sirois, Ph.D | Contact | 418-649-0252 | 66244 | marie-josee.sirois@rea.ulaval.ca |
| Sandrine SH Hegg, Ph.D | Contact | 418-649-0252 | 64293 | ceti.mobility@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Marcel ME Emond, Md, Ph.D | Centre de recherche du CHU de Québec | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Alberta Health Services | Not yet recruiting | Calgary | Alberta | T2N 2T9 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41116303 | Derived | Sirois MJ, Blais J, Aubertin-Leheudre M, Carmichael PH, Fruteau de Laclos L, Desjardins A, Daoust R, Eagles D, Lee J, Perry JJ, Salbach NM, Emond M. Effectiveness of Exercise in Older Adults Discharged From the ER After Minor Injuries: The CEDeComS Stepped-Wedge Trial. J Am Geriatr Soc. 2026 Jan;74(1):74-84. doi: 10.1111/jgs.70166. Epub 2025 Oct 20. | |
| 35305850 |
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| ID | Term |
|---|---|
| D055070 | Resistance Training |
| ID | Term |
|---|---|
| D005081 | Exercise Therapy |
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
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| OTHER |
| Ottawa Hospital Research Institute | OTHER |
| Centre de recherche du Centre hospitalier universitaire de Sherbrooke | OTHER |
| Alberta Health Services, Calgary | OTHER |
| Sunnybrook Research Institute | OTHER |
| Washington University School of Medicine | OTHER |
| McMaster University | OTHER |
| Mount Sinai Hospital, Canada | OTHER |
| The Ottawa Hospital | OTHER |
| Université de Montréal | OTHER |
| University of Ottawa | OTHER |
| Canadian Institutes of Health Research (CIHR) | OTHER_GOV |
This is a step-wedge clinical trial.
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| Changes in mean SOF Frailty index scores at 3 and 6 months after the initial ED visit (from Baseline) | The SOF index is a Frailty measure. Scores range from 0/3 (robust senior) to 3/3 (frail senior) | Outcome measures are assessed at three time points : Baseline T0: time of the Emergency Department (ED) consultation by participants T1: 3 months post-ED consultation; T2: 6 months post-ED consultation |
| Alberta Health Services | Not yet recruiting | Edmonton | Alberta | TG2 2C8 | Canada |
|
| Sunnybrook Health Science Center | Active, not recruiting | Toronto | Ontario | M4N 3M5 | Canada |
| Ottawa Hospital Research Institute | Not yet recruiting | Ottawa | Ontaro | K1Y 4E9 | Canada |
|
| Hôpital Sacré-Coeur | Recruiting | Montreal | Quebec | H4J 1C5 | Canada |
|
| CHU-Québec | Recruiting | Québec | Quebec | G1J 1Z4 | Canada |
|
| Sirois MJ, Carmichael PH, Daoust R, Eagles D, Griffith L, Lang E, Lee J, Perry JJ, Veillette N, Emond M; Canadian Emergency Team Initiative on Mobility in Aging. Functional Decline After Nonhospitalized Injuries in Older Patients: Results From the Canadian Emergency Team Initiative Cohort in Elders. Ann Emerg Med. 2022 Aug;80(2):154-164. doi: 10.1016/j.annemergmed.2022.01.041. Epub 2022 Mar 16. |
| D005791 |
| Patient Care |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |