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Studies have shown the existence of a proprioceptive deficit in patients with Ehlers Danlos Syndrome (EDS) (genetic pathology of connective tissue with hypermobility, multifactor joint instability). A study dating from 2010 showed a qualitative improvement in disability when wearing compression garments (CG) in this pathology, particularly in the fields of proprioception and balance.
The purpose of this study is to quantify the effect of CG on standing static balance in patients with EDS.
To evaluate the effect of CG on standing static balance in patients with EDS, this study is a pilot study, carried out according to a cross-over scheme of type AB/BA.
Each patient will benefit from 2 posturological evaluations, namely without CG (treatment A) and with CG (treatment B). Patients will be randomly assigned to 2 groups: the AB or BA sequence will be randomized for each patient.
For each evaluation, a measurement with eyes open and eyes closed will be performed.
A clinical balance assessment by the Berg test will be performed for each of the conditions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| With compression garments | Active Comparator | Evaluation of the variation in the travel speed of the "center of pressure" with compression garments and the standing static balance. |
|
| Without compression garments | Active Comparator | Evaluation of the variation in the travel speed of the "center of pressure" with compression garments and the standing static balance. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Evaluate the variation in the travel speed of the "center of pressure" with and without compression garments. | Other | Each evaluation will be done according to the following protocol:
|
| Measure | Description | Time Frame |
|---|---|---|
| Evaluate the variation in the travel speed of the "center of pressure" (COP) with compression garments | Each patient will benefit from 2 posturological evaluations, namely without CG (treatment A) and with CG (treatment B). | 15 minutes |
| Evaluate the variation in the travel speed of the "center of pressure" without compression garments. | Evaluate the variation in the travel speed of the "center of pressure" without compression garments. Each patient will benefit from 2 posturological evaluations, namely without CG (treatment A) and with CG (treatment B). | 30 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluate the amplitude of the antero-posterior and lateral oscillations without compression garments | Evaluate the amplitude of the antero-posterior and lateral oscillations of the COP with and without compression garments Compare the stabilometric data with a clinical trial evaluating the reference balance. | 15 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Thomas Van Den Bossche | University Hospital, Toulouse | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Medecine physique et réadaptation | Toulouse | Salies Du Salat | 31260 | France |
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15 patients exposed to the AB sequence and 15 patients exposed to the BA sequence
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|
| Evaluate the amplitude of the antero-posterior and lateral oscillations without compression garments |
Evaluate the amplitude of the antero-posterior and lateral oscillations of the COP with and without compression garments. Compare the stabilometric data with a clinical trial evaluating the reference balance. |
| 30 minutes |
| ID | Term |
|---|---|
| D004535 | Ehlers-Danlos Syndrome |
| ID | Term |
|---|---|
| D020141 | Hemostatic Disorders |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D006474 | Hemorrhagic Disorders |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D012868 | Skin Abnormalities |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D012873 | Skin Diseases, Genetic |
| D030342 | Genetic Diseases, Inborn |
| D003095 | Collagen Diseases |
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D012871 | Skin Diseases |
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