Not provided
Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| L4133 | Other Grant/Funding Number | Italian Ministry of Health |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Data literature lacks of evidence concerning the variation of the nutritional status in patients undergoing hip surgery, thus preventing an effective application a nutritional support program. It is therefore necessary to start identifying the clinical steps (pre-operative and post-operative) that may be defined as critical control points for malnutrition. The observation should foresee the identification of nutritional status indicators, such as weight, hemoglobin, albumin, food intake, and others that might affect a proper recovery. This study aims to investigate the prognostic nutritional factors that might influence clinical outcomes, and their variation in relation to hospitalization and rehabilitation periods.
Data literature lacks of evidence concerning the variation of the nutritional status in patients undergoing hip surgery, thus preventing an effective application a nutritional support program. It is therefore necessary to start identifying the clinical steps (pre-operative and post-operative) that may be defined as critical control points for malnutrition. Patients undergoing hip surgery would be enrolled before the surgical operation and would be evaluated three times: preoperative, postoperative, and after discharge. The observation should foresee the identification of nutritional status indicators, such as weight, hemoglobin, albumin, food intake, and others that might affect a proper recovery. This study aims to investigate the prognostic nutritional factors that might influence clinical outcomes, and their variation in relation to hospitalization and rehabilitation periods.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline level of hemoglobin at 14 days after surgical operation | One of the main decision-making factors that guide the clinician to discharge the patient is the hemoglobin level. The association between preoperative hemoglobin and hemoglobin at discharge was already observed in past orthopedic cohorts, with a loss of 3.3 g/dl being considered clinically relevant. Patients with a better nutritional status may have a reduced fall in hemoglobin after the surgical operation. | Before the surgical operation, after 3 days, after 14 days. |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline level of pre-albumin at 14 days after surgical operation | Pre-albumin (mg/dl) | Before the surgical operation, after 3 days, after 14 days. |
| Change from baseline level of total lymphocyte count at 14 days after surgical operation |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Primary care clinic
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Matteo Briguglio | IRCCS Istituto Ortopedico Galeazzi | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| IRCCS Istituto Ortopedico Galeazzi | Milan | Italy |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D044342 | Malnutrition |
| D000740 | Anemia |
| ID | Term |
|---|---|
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Total lymphocyte count (cells/mm^3)
| Before the surgical operation, after 3 days, after 14 days. |
| Change from baseline level of iron at 14 days after surgical operation | Iron (μg/dl) | Before the surgical operation, after 3 days, after 14 days. |
| Change from baseline level of vitamin D at 14 days after surgical operation | 25[OH]D (ng/ml) | Before the surgical operation, after 3 days, after 14 days. |
| Change from baseline of weight 14 days after surgical operation | Weight (kg) | Before the surgical operation, after 3 days, after 14 days. |
| Change from baseline of calf circumference 14 days after surgical operation | Calf circumference (cm) | Before the surgical operation, after 3 days, after 14 days. |
| Change from baseline of % of fat mass at 14 days after surgical operation | Bioelectrical impedance analysis (% of fat mass and % of lean mass) | Before the surgical operation, after 3 days, after 14 days. |
| Change from baseline of hand-grip strength at 14 days after surgical operation | Hand-grip strength (kg). For this test, the higher values, the better is. | Before the surgical operation, after 3 days, after 14 days. |
| Change from baseline of FIM test at 14 days after surgical operation | Functional Independence Measure (FIM) (18-126 point scale). For this test, the higher values, the better is. | Before the surgical operation, after 3 days, after 14 days. |
| Change from baseline of 10 meter walking test at 14 days after surgical operation | 10 meter walking test (m/s). For this test, the higher values, the better is. | Before the surgical operation, after 3 days, after 14 days. |
| Change from baseline of POMA at 14 days after surgical operation | Performance Oriented Mobility Assessment (POMA) (0-32 point scale). For this test, the higher values, the better is. | Before the surgical operation, after 3 days, after 14 days. |