Objective and Principle: To evaluate whether enlarging the incision can reduce corneal complications associated with phacoemulsification with regular 2.2 mm incision.

The aim of this study: To evaluate whether the technique of enlarging internal incision could reduce the incidence of descemet membrane detachment after 2.2 mm incision phacoemulsification.

Secondary outcome: To evaluate whether the technique of enlarged internal incision can reduce other corneal complications such as corneal edema and astigmatism after 2.2 mm incision phacoemulsification.

Study Design: A prospective randomized controlled study

Inclusion Criteria:

• Age-related cataract patients
• Age from 65 to 90
• The diameter of pupil after mydriasis is more than 6 mm
• LOCS III nuclear grade ≥4
• Corneal endothelial cell count > 1500 cells/mm2
• Phacoemulsification and intraocular lens implantation are planned
• Agree to participate in this study and sign informed consent

Exclusion Criteria:

• History of ocular trauma
• Anterior segment lesions (exfoliation syndrome, suspension ligament injury or relaxation, corneal and iris lesions, glaucoma)
• Other ocular diseases that impair visual function, such as optic neuropathy, uveitis and ocular tumors
• History of Ophthalmic Surgery
• Intraoperative and Postoperative Complications