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| ID | Type | Description | Link |
|---|---|---|---|
| 2018-A00702-53 | Other Identifier | Registry ID: ID RCB |
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the purpose of this study is to evaluate the cryotherapy effect by vapocoolant spray to reducing pain during puncture for artérial blood gas
Blood gas analysis by arterial puncture is the Gold Standard in the assessment of a patient's acidbase status and oxygenation. This procedure, which can be repeated depending on the clinical condition of patient, is however associated with a potentially painful experience for patients.
The known anesthetic properties of cold can be an interesting alternative to evaluate in the reduction of pain induced during arterial puncture for gas analysis in critically il patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| cryotherapy group | Experimental | cryotherapy by vapocoolant spray is applied on skin for 4 to 10 seconds ( or up to skin whitening) to 15 centimeters distance with sweeping action before ABG |
|
| control group | Placebo Comparator | water spray is applied on skin for 4 to 10 seconds to centimeters distance with sweeping action before ABG |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cryotherapy | Device | patients recieving cryotherapy for skin anesthesia for artérial blood gas |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain during arterial puncture | Pain will be assessed with the visual analog scale (numeric value go 0 to 100 millimeters and representing intensity of pain from "no pain" to "worst pain imaginable"(1) | immediately after puncture |
| Measure | Description | Time Frame |
|---|---|---|
| Ease to performing Arterial Blood Gas (ABG) sampling | Ease to performing ABG sampling will be evaluated by i)the number of punctures necessary to obtain a sample of at least 1ml of arterial blood, ii) the delay between the first arterial puncture, and obtaining a sample. | immediately after puncture |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Gwenaëlle Jacq, RN | CH Versailles | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hopital Nord Franche-Comte | Belfort | 90015 | France | |||
| Ch Versailles |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41996883 | Result | Jacq G, Minghetti F, Souppart V, Labreuche J, Aegerter P, Chauvin V, Legriel S. Efficacy of local cryoanalgesia by vapocoolant spray on pain induced by arterial puncture in critically ill patients: A multicentre randomised controlled trial (SNOW study). Aust Crit Care. 2026 Jun;39(3):101581. doi: 10.1016/j.aucc.2026.101581. Epub 2026 Apr 17. |
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| ID | Term |
|---|---|
| D017679 | Cryotherapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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| Le Chesnay |
| 78150 |
| France |
| CHU Saint LOUIS | Paris | 75010 | France |
| Hopital Européèn Georges Pompidou | Paris | 75015 | France |