Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy

Long-term Observation of Symptomatic Women With Uterine Fibroids Who Have Been Treated With Ulipristal Acetate: Findings on Symptomatology, Morphological Structure, Endometrial Patterns

A prospective observational study on italian women undergoing ulipristal acetate (uPa) therapy for symptomatic myomas and its impact on symptomatology and moreover on myomas architecture. We also evaluate changes in the endometrial pattern of selected women.

Inclusion Criteria:

• number of myomas from 1 to 4
• heavy menstrual bleeding
• conservative treatment request

Exclusion Criteria:

• concurrent endometrial pathology
• post-menopausal status
• hepatic pathology
• endocrine or metabolic disorders