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Septic pseudarthrosis of long bones are complications that can unfortunately occur after the consolidation of a fracture and some situations present risks of superinfection, persistent infection or mechanical failure (30-40% risk of complications) that can lead to amputation.
A possible saving situation used by CRIOAC ("Centre de Référence des Infections Ostéo-Articulaires Complexes") is the use of a bone substitute impregnated with an antibiotic allowing a high local concentration of this antibiotic.
The aim of this study is to evaluate the cost of management of septic pseudarthrosis with two-stage treatment and CERAMENT® and the quality of life for this patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CERAMENT | Patients having a septic pseudarthrosis managed with two-stage treatment (Masquelet Technique) with CERAMENT®. |
| |
| NO CERAMENT COMPARATIVE COHORT | Patients having had a septic pseudarthrosis managed with two-stage treatment (only Masquelet Technique) without CERAMENT®. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cost evaluation | Other | The cost for the hospital of the strategy of management will be evaluated. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Cost evaluation | Estimation of the cost of care from the point of view of the hospital This estimation will be measured at the end of patient follow-up (usually between 12 and 24 months after antibiotic therapy disruption) | 24 months maximum |
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Inclusion Criteria:
Exclusion Criteria:
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Patients having / having had a septic pseudarthrosis manage with two stage exchange (Masquelet technique)
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre de Référence des Infections Ostéo-Articulaires complexes (CRIOAc) - Hôpital de la Croix-Rousse | Lyon | 69317 | France |
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| Questionnaire | Other | The quality of life of patients will be measured. |
|
| ID | Term |
|---|---|
| D011542 | Pseudarthrosis |
| ID | Term |
|---|---|
| D005599 | Fractures, Ununited |
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
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| ID | Term |
|---|---|
| D003362 | Cost-Benefit Analysis |
| D011795 | Surveys and Questionnaires |
| ID | Term |
|---|---|
| D003365 | Costs and Cost Analysis |
| D004467 | Economics |
| D004472 | Health Care Economics and Organizations |
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
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