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Klebsiella pneumoniae is implicated in the occurrence of severe pneumonia. Most Klebsiella pneumoniae infections are associated with care and occur in patients with compromised immune defenses. More recently, cases of hepatic abscess and acute community meningitis related to strains of Klebsiella pneumoniae have been reported. The mortality of these infections is important, most often due to a delayed diagnosis. The poor prognostic factors reported in the literature for very low numbers are: advanced age, coma, septic shock, glyceryachia <10mg / dL and proteinuria> 750 mg / dL. In addition, no study has specifically focused on the factors of occurrence and factors associated with Klebsiella sp. Indeed, meningitis related to Klebsiella pneumoniae seems to be a rare but probably underestimated event whose risk factors, clinical presentation, microbiological are little known and the treatment modalities of this severe infection are not codified.
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| Measure | Description | Time Frame |
|---|---|---|
| Characterize meningitis with Klebsiella pneumoniae | This corresponds to characterize Klebsiella pneumoniae meningitis, portal entry, secondary infection, associated antibiotic and associated therapies and the clinical course of patients. | Day 1 |
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Inclusion Criteria:
Exclusion Criteria:
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Patient with meningitis Klebsiella sp., hospitalized in one of the hospitals of the Clinical Microbiology Group between 2008 and 2018.
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| Name | Affiliation | Role |
|---|---|---|
| Benoit PILMIS, MD | Fondation Hôpital Saint-Joseph | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Brest | Brest | France | ||||
| CHU Caen |
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| Caen |
| France |
| Hôpital henri Mondor | Créteil | France |
| CHU Lyon | Lyon | France |
| CHU Nantes | Nantes | 44093 | France |
| CHU Nice | Nice | France |
| Hôpital Lariboisière | Paris | 75010 | France |
| Groupe Hospitalier Paris Saint-Joseph | Paris | 75014 | France |
| Hôpital Cochin | Paris | 75014 | France |
| CHU Kremlin Bicetre | Paris | France |
| Hôpital Foch | Paris | France |
| Hôpital Necker Enfants Malades | Paris | France |
| Hôpital Sainte Anne | Paris | France |
| CHU Poitiers | Poitiers | 86000 | France |
| CHU Reims | Reims | France |
| CHU Rennes | Rennes | 35000 | France |
| CHU Strasbourg | Strasbourg | 67000 | France |
| CHU Tours | Tours | France |
| ID | Term |
|---|---|
| D008581 | Meningitis |
| ID | Term |
|---|---|
| D000090862 | Neuroinflammatory Diseases |
| D009422 | Nervous System Diseases |
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