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This study characterizes heart failure patients who attended the University Hospital Würzburg. The primary aim is a better understanding of the relationships and differences between the subgroups HFrEF (EF < 40%), HFmrEF (EF 40-49%), and HFpEF (EF>50%), contributing to an improved diagnosis, prognosis and therapy of patients with heart failure.
The varying clinical picture of heart failure (HF) represents a major challenge for patient care in Germany. HF is one of the most common reasons for hospitalization in the Western world. In the chronic course of heart failure, affected patients are committed to morbidity, lifelong therapy and high risk of cardiac decompensation, also associated with high mortality.
Heart failure patients, who visited the Cardiology Department of the University Hospital Wuerzburg, shall be analyzed with regard to all clinical data and outcome. This retrospective work should help to better understand the three groups HFrEF (EF < 40%), HFmrEF (EF 40-49%) and HFpEF (EF>50%) and help identifying similarities and differences between the groups.
Hereby we hope for progress in diagnostic, prognostic and therapeutic aspects of heart failure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HFrEF | HFrEF (Heart failure with reduced ejection fraction): ESC Guideline heart failure 2016: patients with LVEF < 40%. LVEF = Left ventricular ejection fraction |
| |
| HFmrEF | HFmrEF (Heart failure with mid-range reduced ejection fraction): ESC Guideline heart failure 2016: patients with LVEF 40-49%. LVEF = Left ventricular ejection fraction |
| |
| HFpEF | HFmrEF (Heart failure with preserved ejection fraction): ESC Guideline heart failure 2016: patients with LVEF > 50%. LVEF = Left ventricular ejection fraction |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Time (outcome) | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Long-term survival in heart failure patients with preserved, mid-range or reduced left ventricular ejection fraction | Survival of patients with heart failure extracted from medical record or by telephone interview | 1 year follow up after last examination |
| Measure | Description | Time Frame |
|---|---|---|
| Impact of clinical imaging and laboratory parameters on long-term survival in heart failure patients with precerved, mid-range or reduced left ventricular ejection fraction | Parameters are derived from standard echocardiography, cardiac magnetic resonance imaging and blood testing. | 6 months |
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Inclusion Criteria:
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Our cohort consists of patients who attended the Cardiology Department of University Hospital Wuerzburg in the time period between 2009 and 2019.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Peter Nordbeck, MD, PhD | Contact | +49 931 201 39181 | nordbeck_p@ukw.de | |
| Kai Hu, MD | Contact | +49 931 201 0 | hu_k@ukw.de |
| Name | Affiliation | Role |
|---|---|---|
| Peter Nordbeck, MD, PhD | Wuerzburg University Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Würzburg | Recruiting | Würzburg | Bavaria | 97080 | Germany |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D013995 | Time |
| ID | Term |
|---|---|
| D055585 | Physical Phenomena |
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